Article: 1-Arylsulfonyl-2-(pyridylmethylsulfinyl) benzimidazoles as new proton pump inhibitor prodrugs

New arylsulfonyl proton pump inhibitor (PPI) prodrug forms were synthesized. These prodrugs provided longer residence time of an effective PPI plasma concentration, resulting in better gastric acid inhibition.

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1-Arylsulfonyl-2-(pyridylmethylsulfinyl) Benzimidazoles As New Proton Pump Inhibitor Prodrugs