George Sachs
Overview
Explore the profile of George Sachs including associated specialties, affiliations and a list of published articles.
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Articles
103
Citations
2998
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Recent Articles
1.
LaBarbera V, Gill E, Hill N, Sachs G
R I Med J (2013)
. 2024 Jun;
107(7):51-53.
PMID: 38917317
No abstract available.
2.
Knouse L, Hu X, Sachs G, Isaacs S
PLOS Digit Health
. 2023 Feb;
1(8):e0000083.
PMID: 36812621
Objective: Cognitive-behavioral therapy (CBT) has growing evidence of efficacy for Attention-Deficit/Hyperactivity Disorder (ADHD) in adults. Mobile health apps are promising tools for delivering scalable CBT. In a 7-week open study...
3.
Sarezky J, Sachs G, Elinzano H, Stavros K
Clin Geriatr Med
. 2021 Apr;
37(2):289-300.
PMID: 33858611
Patients with cancer may experience neuropathy at any stage of malignancy, ranging from symptoms that are the earliest signs of cancer to side effects of treatment. Peripheral nerves are affected...
4.
Cui Y, Zhou K, Strugatsky D, Wen Y, Sachs G, Zhou Z, et al.
Sci Adv
. 2019 Mar;
5(3):eaav8423.
PMID: 30906870
The urea channel of (UreI) is an ideal drug target for preventing gastric cancer but incomplete understanding of its gating mechanism has hampered development of inhibitors for the eradication of...
5.
Scott D, Sachs G, Marcus E
F1000Res
. 2018 Jul;
5.
PMID: 30023042
Infection of the stomach by the gastric pathogen results in chronic active gastritis and leads to the development of gastric and duodenal ulcer disease and gastric adenocarcinoma. Eradication of infection...
6.
Wen Y, Scott D, Vagin O, Tokhtaeva E, Marcus E, Sachs G
J Bacteriol
. 2018 May;
200(14).
PMID: 29735759
is an organism known to colonize the normal human stomach. Previous studies have shown that the bacterium does this by elevating its periplasmic pH via the hydrolysis of urea. However,...
7.
Marcus E, Sachs G, Scott D
Helicobacter
. 2018 Apr;
23(3):e12490.
PMID: 29696729
Background: The pathogen Helicobacter pylori encounters many stressors as it transits to and infects the gastric epithelium. Gastric acidity is the predominate stressor encountered by the bacterium during initial infection...
8.
Abe K, Shimokawa J, Naito M, Munson K, Vagin O, Sachs G, et al.
Sci Rep
. 2017 Jul;
7(1):6632.
PMID: 28747707
The gastric proton pump H,K-ATPase acidifies the gastric lumen, and thus its inhibitors, including the imidazo[1,2-a]pyridine class of K-competitive acid blockers (P-CABs), have potential application as acid-suppressing drugs. We determined...
9.
Reynolds J, Sachs G, Stavros K
R I Med J (2013)
. 2016 Dec;
99(12):32-35.
PMID: 27902997
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired immune-mediated disorder characterized by weakness and sensory deficits that can lead to significant neurological disability. The diagnosis is based on a combination...
10.
Habeck M, Tokhtaeva E, Nadav Y, Ben Zeev E, Ferris S, Kaufman R, et al.
J Biol Chem
. 2016 Sep;
291(44):23159-23174.
PMID: 27624940
The Na,K-ATPase α subunit plays a key role in cardiac muscle contraction by regulating intracellular Ca, whereas α has a more conventional role of maintaining ion homeostasis. The β subunit...