Air-stable Secondary Phosphine Oxide As Preligand for Palladium-catalyzed Intramolecular Alpha-arylations with Chloroarenes

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2009 Sep 25

PMID 19775182

Citations 7

Authors

Lutz Ackermann

Ruben Vicente

Nora Hofmann

Affiliations

Soon will be listed here.

Abstract

A palladium catalyst derived from air-stable secondary phosphine oxide (1-Ad)(2)P(O)H enabled efficient intramolecular alpha-arylations of amides with aryl chlorides, which allowed for the synthesis of diversely substituted (aza)oxindoles.

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