Alpha-arylation of 3-aryloxindoles

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2010 Apr 30

PMID 20426400

Citations 5

Authors

Cheng-Kang Mai

Matthew F Sammons

Tarek Sammakia

Affiliations

Soon will be listed here.

Abstract

A versatile method for the synthesis of 3,3-diaryloxindoles via Pd-catalyzed alpha-arylations or an S(N)Ar reaction is described. The reaction proceeds using mild base, is tolerant of a variety of functional groups, and is capable of preparing hindered all-carbon quaternary centers.

Citing Articles

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Transition-metal-free α-arylation of oxindoles a visible-light-promoted electron transfer.

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Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone.

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