IL9 Maps to Mouse Chromosome 13 and Human Chromosome 5

Overview

Journal Immunogenetics

Specialties Allergy & Immunology
Genetics

Date 1990 Jan 1

PMID 1970335

Citations 17

Authors

B A Mock

M Krall

C A Kozak

M N Nesbitt

O W MCBRIDE

J C Renauld

J Van Snick

Affiliations

Soon will be listed here.

Abstract

Mouse and human cDNA clones encoding the T-cell and mast cell growth factor P40, now designated IL-9, were used to identify DNA restriction fragment length polymorphisms (RFLPs) in sets of somatic cell hybrids and between inbred strains of mice and interspecific backcross progeny. Segregation of mouse and human chromosomes among somatic cell hybrids indicated a location on mouse chromosome 13 and human chromosome 5. RFLPs were identified among inbred strains of mice. Analysis of chromosome 13 alleles for Tcrg, Dhfr, and Il-9 in an interspecific cross between Mus musculus and NFS/N or C58/J mice indicates that IL9 is distal to Tcrg and proximal to Dhfr.

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