» Articles » PMID: 19652939

Pathophysiology of Burns

Overview
Specialty General Medicine
Date 2009 Aug 5
PMID 19652939
Citations 31
Authors
Affiliations
Soon will be listed here.
Abstract

Burn injury represents a significant problem worldwide. Advances in therapy strategies, based on better understanding of the pathophysiologic responses after burn injury have improved the clinical outcome of patients with burn injuries over the past years. This article describes the present understanding of the pathophysiology of a burn injury including both the local and systemic responses, focusing on the many facets of organ and systemic effects directly resulting from hypovolemia and circulating mediators following burn trauma.

Citing Articles

Investigation of the Effect of Camellia Sinensis Essence Cream on Skin Burns.

Mercantepe T, Yilmaz A, Topcu A, Bilgin A, Tumkaya L, Mercantepe F Life (Basel). 2025; 15(2).

PMID: 40003585 PMC: 11856605. DOI: 10.3390/life15020176.


The Accuracy of Prehospital Fluid Resuscitation of Burn Patients: A Systematic Review.

Alsaqabi F, Ahmed Z Eur Burn J. 2024; 3(4):517-526.

PMID: 39600018 PMC: 11571815. DOI: 10.3390/ebj3040044.


Retrospective Study of the Epidemiological-Clinical Characteristics of Burns Treated in a Hospital Emergency Service (2018-2022).

Alcala-Cerrillo M, Gonzalez-Sanchez J, Gonzalez-Bernal J, Santamaria-Pelaez M, Fernandez-Solana J, Sanchez Gomez S Nurs Rep. 2024; 14(3):1987-1997.

PMID: 39189278 PMC: 11348191. DOI: 10.3390/nursrep14030148.


Dexmedetomidine on the interplay of IL-6 and STAT3 pathways in adrenal gland damage-induced scalding burns in rats.

Ciftel S, Mercantepe F, Mercantepe T, Ciftel E, Klisic A Naunyn Schmiedebergs Arch Pharmacol. 2024; 398(1):641-655.

PMID: 39042159 PMC: 11787240. DOI: 10.1007/s00210-024-03300-7.


Unforeseen Heat: An Accidental Superficial Partial-Thickness Hand Burn Utilizing a New Convection Oven.

Canatan M, Canatan A, Canatan M Cureus. 2023; 15(7):e42641.

PMID: 37644946 PMC: 10462380. DOI: 10.7759/cureus.42641.


References
1.
Tokyay R, Zeigler S, Traber D, Stothert Jr J, Loick H, Heggers J . Postburn gastrointestinal vasoconstriction increases bacterial and endotoxin translocation. J Appl Physiol (1985). 1993; 74(4):1521-7. DOI: 10.1152/jappl.1993.74.4.1521. View

2.
Fink M . Gastrointestinal mucosal injury in experimental models of shock, trauma, and sepsis. Crit Care Med. 1991; 19(5):627-41. DOI: 10.1097/00003246-199105000-00009. View

3.
Leape I . Kinetics of burn edema formation in primates. Ann Surg. 1972; 176(2):223-6. PMC: 1355309. DOI: 10.1097/00000658-197208000-00018. View

4.
Ward P, Till G . Pathophysiologic events related to thermal injury of skin. J Trauma. 1990; 30(12 Suppl):S75-9. DOI: 10.1097/00005373-199012001-00018. View

5.
Bauer J, Hafner M, Fritz H . Balanced antiinflammation: the combined application of a PAF inhibitor and a cyclooxygenase inhibitor blocks the inflammatory take-off after burns. Int J Tissue React. 1990; 12(4):203-11. View