Point Mutation Rate of Bacteriophage PhiX174

Overview

Journal Genetics

Publisher Oxford University Press

Specialty Genetics

Date 2009 Aug 5

PMID 19652180

Citations 19

Authors

Jose M Cuevas

Siobain Duffy

Rafael Sanjuan

Affiliations

Soon will be listed here.

Abstract

The point mutation rate of phage PhiX174 was determined using the fluctuation test. After identifying the genetic changes associated with the selected phenotype, we obtained an estimate of 1.0x10(-6) substitutions per base per round of copying, which is consistent with Drake's rule (0.003 mutations per genome per round of copying in DNA-based microorganisms).

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