Rafael Sanjuan
Overview
Explore the profile of Rafael Sanjuan including associated specialties, affiliations and a list of published articles.
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Articles
146
Citations
4462
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Recent Articles
1.
Arce R, Sonora M, Andreu-Moreno I, Moreno P, Moratorio G, Sanjuan R
Sci Rep
. 2025 Mar;
15(1):8314.
PMID: 40064995
Coxsackievirus B3 (CVB3), a member of the Enterovirus genus within the Picornaviridae family, has emerged as a key model for studying viral evolution and pathogenesis. Although traditionally considered obligate lytic...
2.
Buigues J, Vinals A, Martinez-Recio R, Monros J, Sanjuan R, Cuevas J
Viruses
. 2025 Jan;
16(12.
PMID: 39772193
Viromics studies are allowing us to understand not only the enormous diversity of the virosphere, but also the potential threat posed by the emerging viruses. Regarding the latter, the main...
3.
Dufloo J, Andreu-Moreno I, Moreno-Garcia J, Valero-Rello A, Sanjuan R
Nat Microbiol
. 2025 Jan;
10(2):405-419.
PMID: 39747691
Cross-species transmission of animal viruses poses a threat to human health. However, systematic experimental assessments of these risks remain scarce. A critical step in viral infection is cellular internalization mediated...
4.
Larrieux A, Sanjuan R
Sci Rep
. 2024 Nov;
14(1):27209.
PMID: 39516525
Oncolytic virotherapy has shown efficacy in various animal models and a few human cancers. However, there are still significant limitations for the implementation of these therapies. One such limitation is...
5.
Buigues J, Vinals A, Martinez-Recio R, Monros J, Cuevas J, Sanjuan R
Proc Natl Acad Sci U S A
. 2024 Oct;
121(45):e2415631121.
PMID: 39471221
Reverse-transcribing animal DNA viruses include the hepadnaviruses, a well-characterized family of small enveloped viruses that infect vertebrates but also a sister group of nonenveloped viruses more recently discovered in fish...
6.
Ferriol-Gonzalez C, Concha-Eloko R, Bernabeu-Gimeno M, Fernandez-Cuenca F, Canada-Garcia J, Garcia-Cobos S, et al.
Microbiol Spectr
. 2024 Aug;
12(10):e0025424.
PMID: 39194291
is one of the most threatening multi-drug-resistant pathogens today, with phage therapy being a promising alternative for personalized treatments. However, the intrinsic capsule diversity in spp. poses a substantial barrier...
7.
Carrascosa-Saez M, Buigues J, Vinals A, Andreu-Moreno I, Martinez-Recio R, Soriano-Tordera C, et al.
Virol J
. 2024 Aug;
21(1):193.
PMID: 39175061
Background: Emerging zoonotic diseases arise from cross-species transmission events between wild or domesticated animals and humans, with bats being one of the major reservoirs of zoonotic viruses. Viral metagenomics has...
8.
DepoScope: Accurate phage depolymerase annotation and domain delineation using large language models
Concha-Eloko R, Stock M, De Baets B, Briers Y, Sanjuan R, Domingo-Calap P, et al.
PLoS Comput Biol
. 2024 Aug;
20(8):e1011831.
PMID: 39102416
Bacteriophages (phages) are viruses that infect bacteria. Many of them produce specific enzymes called depolymerases to break down external polysaccharide structures. Accurate annotation and domain identification of these depolymerases are...
9.
Buigues J, Vinals A, Martinez-Recio R, Monros J, Sanjuan R, Cuevas J
Microbiol Spectr
. 2024 Jul;
12(8):e0067524.
PMID: 38990026
Importance: Metagenomics has become a fundamental tool to characterize the global virosphere, allowing us not only to understand the existing viral diversity and its ecological implications but also to identify...
10.
Marques M, Andreu-Moreno I, Sanjuan R, Elena S, Geller R
Sci Rep
. 2024 Jun;
14(1):14644.
PMID: 38918479
Viral glycoproteins mediate entry into host cells, thereby dictating host range and pathogenesis. In addition, they constitute the principal target of neutralizing antibody responses, making them important antigens in vaccine...