Efficacy of Emodepside Plus Praziquantel Tablets (Profender Tablets for Dogs) Against Mature and Immature Adult Ancylostoma Caninum and Uncinaria Stenocephala Infections in Dogs

Overview

Journal Parasitol Res

Specialty Parasitology

Date 2009 Jul 4

PMID 19575220

Citations 7

Authors

Annette Schimmel

Gertraut Altreuther

Iris Schroeder

Samuel Charles

Larry Cruthers

Jennifer Ketzis

Dawid J Kok

Friederike Kraemer

John W McCall

Klemens J Krieger

Affiliations

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Abstract

This paper reports the efficacy of a novel flavoured tablet formulation of emodepside plus praziquantel (Profender tablets for dogs) against mature and immature adult hookworms (Ancylostoma caninum and Uncinaria stenocephala) in dogs. The tablets were used at the minimum recommended dose of 1 mg emodepside and 5 mg praziquantel per kg body weight. Four randomised, blinded and controlled laboratory studies demonstrated >95% efficacy against mature and immature adult stages of U. stenocephala and four randomised, blinded and controlled laboratory studies demonstrated >98% efficacy against mature and immature adult stages of A. caninum. No side effects of the treatment were observed. It is concluded that the emodepside plus praziquantel tablet is an effective and safe treatment against mature and immature hookworms.

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References

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Altreuther G, Schimmel A, Schroeder I, Bach T, Charles S, Kok D . Efficacy of emodepside plus praziquantel tablets (Profender tablets for dogs) against mature and immature infections with Toxocara canis and Toxascaris leonina in dogs. Parasitol Res. 2009; 105 Suppl 1:S1-8. DOI: 10.1007/s00436-009-1489-7. View

Schimmel A, Altreuther G, Schroeder I, Charles S, Cruthers L, Kok D . Efficacy of emodepside plus praziquantel tablets (Profender tablets for dogs) against mature and immature adult Trichuris vulpis infections in dogs. Parasitol Res. 2009; 105 Suppl 1:S17-22. DOI: 10.1007/s00436-009-1491-0. View

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