What Do Diffusion Measurements Tell Us About Membrane Compartmentalisation? Emergence of the Role of Interprotein Interactions
Overview
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The techniques of diffusion analysis based on optical microscopy approaches have revealed a great diversity of the dynamic organisation of cell membranes. For a long period, two frameworks have dominated the way of representing the membrane structure: the membrane skeleton fences and the lipid raft models. Progresses in the methods of data analysis have shed light on the features and consequently the possible origin of membrane domains: Inter-protein interactions play a role in confinement. Innovative developments pushing forward the spatiotemporal resolution limits are currently emerging, which are likely to provide in the future a detailed understanding of the intimate functional dynamic organisation of the cell membrane.
Liu H, Capuani S, Badachhape A, Di Trani N, Davila Gonzalez D, Vander Pol R Bioeng Transl Med. 2023; 8(6):e10594.
PMID: 38023719 PMC: 10658527. DOI: 10.1002/btm2.10594.
Exploring the influence of cytosolic and membrane FAK activation on YAP/TAZ nuclear translocation.
Eroume K, Cavill R, Stankova K, de Boer J, Carlier A Biophys J. 2021; 120(20):4360-4377.
PMID: 34509508 PMC: 8553670. DOI: 10.1016/j.bpj.2021.09.009.
High-Precision Protein-Tracking With Interferometric Scattering Microscopy.
Taylor R, Holler C, Mahmoodabadi R, Kuppers M, Dastjerdi H, Zaburdaev V Front Cell Dev Biol. 2020; 8:590158.
PMID: 33224953 PMC: 7669747. DOI: 10.3389/fcell.2020.590158.
Beg A, Khan A Biophys Rev. 2020; 12(5):1249-1256.
PMID: 32930961 PMC: 7575677. DOI: 10.1007/s12551-020-00759-5.
He W, Su Y, Peng H, Tong P Mol Biol Cell. 2020; 31(13):1380-1391.
PMID: 32348189 PMC: 7353135. DOI: 10.1091/mbc.E19-08-0473.