Guang-Ho Cha
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Explore the profile of Guang-Ho Cha including associated specialties, affiliations and a list of published articles.
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52
Citations
1141
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Recent Articles
1.
Kim B, Choi H, Lee J, Choi I, Yuk J, Cha G, et al.
Parasites Hosts Dis
. 2025 Mar;
63(1):37-49.
PMID: 40045679
Cancer immunotherapy is widely used to treat various cancers to augment the weakened host immune response against tumors. Dendritic cells (DCs) are specialized antigen-presenting cells that play dual roles in...
2.
Lee H, Ham D, Seo S, Cha G, Shin E
Parasites Hosts Dis
. 2024 Dec;
62(4):408-423.
PMID: 39622653
Toxoplasma gondii primarily invades the central nervous system, causing latent infections. Cysts persist in the host for life and there is currently no effective treatment. T. gondii infects human hosts...
3.
Neupane C, Sharma R, Gao F, Pham T, Kim Y, Yoon B, et al.
J Neurosci
. 2024 Sep;
44(41.
PMID: 39227159
Targeting altered expression and/or activity of GABA (γ-aminobutyric acid) transporters (GATs) provide therapeutic benefit for age-related impairments, including cognitive dysfunction. However, the mechanisms underlying the transcriptional regulation of GATs are...
4.
Lee J, Ko Y, Choi Y, Kim J, Cho H, Choi H, et al.
Nutrients
. 2024 Mar;
16(5).
PMID: 38474770
Sepsis, a leading cause of death worldwide, is a harmful inflammatory condition that is primarily caused by an endotoxin released by Gram-negative bacteria. Effective targeted therapeutic strategies for sepsis are...
5.
Quan J, Gao F, Ma T, Ye W, Gao X, Deng M, et al.
Am J Pathol
. 2023 Sep;
193(12):2047-2065.
PMID: 37741453
Toxoplasma gondii infection in pregnant women may cause fetal anomalies; however, the underlying mechanisms remain unclear. The current study investigated whether T. gondii induces pyroptosis in human placental cells and...
6.
Lee J, Yuk J, Cha G, Lee Y
Parasites Hosts Dis
. 2023 May;
61(2):138-146.
PMID: 37258260
Toxoplasma gondii is an intracellular protozoan parasite which can infect most warm-blooded animals and humans. Among the different mouse models, C57BL/6 mice are more susceptible to T. gondii infection compared...
7.
Lee J, Kim J, Lee J, Choi Y, Choi H, Cho H, et al.
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36362370
Sirtuin 1 (SIRT1) regulates cellular processes by deacetylating non-histone targets, including transcription factors and intracellular signalling mediators; thus, its abnormal activation is closely linked to the pathophysiology of several diseases....
8.
Gao F, Quan J, Lee M, Ye W, Yuk J, Cha G, et al.
Parasit Vectors
. 2021 Dec;
14(1):603.
PMID: 34895315
Background: Trichomonas vaginalis causes lesions on the cervicovaginal mucosa in women; however, its pathogenesis remains unclear. We have investigated the involvement of the endoplasmic reticulum (ER) in the induction of...
9.
FAF1 downregulation by Toxoplasma gondii enables host IRF3 mobilization and promotes parasite growth
Gao F, Quan J, Choi I, Lee Y, Jang S, Yuk J, et al.
J Cell Mol Med
. 2021 Aug;
25(19):9460-9472.
PMID: 34464509
Fas-associated factor 1 (FAF1) has gained a reputation as a member of the FAS death-inducing signalling complex. However, the role of FAF1 in the immunity response is not fully understood....
10.
Quan J, Gao F, Chu J, Cha G, Yuk J, Wu W, et al.
Nanomedicine (Lond)
. 2021 May;
16(16):1357-1375.
PMID: 34008419
To investigate the anticancer mechanisms of silver nanoparticles (AgNPs) in colorectal cancer. Anticancer effects of AgNPs were determined in colorectal cancer HCT116 cells and xenograft mice using cellular and molecular...