Chronic Pelvic Pain Syndromes: Clinical, Urodynamic, and Urothelial Observations

Overview

Journal Int Urogynecol J Pelvic Floor Dysfunct

Specialties Gynecology & Obstetrics
Urology

Date 2009 May 22

PMID 19458891

Citations 10

Authors

Charles W Butrick

Dan Sanford

Qingijiang Hou

Jonathan D Mahnken

Affiliations

Soon will be listed here.

Abstract

Introduction/methods: A cohort of 408 patients with bladder pain syndrome/interstitial cystitis (BPS/IC) was evaluated, and findings were discussed in this retrospective chart review.

Results: Based on the chief complaints, they were divided into four subgroups: BPS/IC (n = 157), CPP (n = 98), vulvodynia/dyspareunia (n = 40), and "other" (n = 113). Similar findings were found in all four subgroups: complaints of voiding dysfunction (70%), dyspareunia (54%), mean PUF score of 15.9 +/- 6.4, and a positive potassium sensitivity test in 83%. Urodynamics revealed a maximal urethral pressure of 131 cm of water and an abnormal uroflow in 80%. Urothelial therapy in the form of intravesical therapeutic anesthetic cocktails provided benefit in all groups (50%, 67%, 73%, and 77% for vulvodynia, CPP, BPS/IC, "other").

Conclusions: All subgroups had similar findings and response to therapy. Five to 10% of patients with chief complaints of stress or urge incontinence or prolapse were also found to have BPS/IC.

Citing Articles

Non-Hunner's Interstitial Cystitis Is Different from Hunner's Interstitial Cystitis and May Be Curable by Uterosacral Ligament Repair.

Goeschen K, Gold D, Liedl B, Yassouridis A, Petros P Urol Int. 2022; 106(7):649-657.

PMID: 35512665 PMC: 9393835. DOI: 10.1159/000524321.

Diagnostic Value of the Maximum Urethral Closing Pressure in Women With Overactive Bladder Symptoms and Functional Bladder Outlet Obstruction.

Kim S, Choo H, Yoon H Int Neurourol J. 2022; 26(Suppl 1):S1-7.

PMID: 35236047 PMC: 8896775. DOI: 10.5213/inj.2040482.241.

Vulvodynia: a neuroinflammatory pain syndrome originating in pelvic visceral nerve plexuses due to mechanical factors.

Bornstein J, Palzur E, Swash M, Petros P Arch Gynecol Obstet. 2022; 306(5):1411-1415.

PMID: 35147761 PMC: 9519726. DOI: 10.1007/s00404-022-06424-4.

CUA guideline: Diagnosis and treatment of interstitial cystitis/bladder pain syndrome.

Cox A, Golda N, Nadeau G, Nickel J, Carr L, Corcos J Can Urol Assoc J. 2016; 10(5-6):E136-E155.

PMID: 27790294 PMC: 5065402. DOI: 10.5489/cuaj.3786.

The integral system.

Petros P Cent European J Urol. 2014; 64(3):110-9.

PMID: 24578877 PMC: 3921723. DOI: 10.5173/ceju.2011.03.art1.

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