Is Calcium Supplementation a Risk Factor for Cardiovascular Diseases in Older Women?
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Low intake of dietary calcium is related to bone loss and fragility fracture in older adults, especially postmenopausal women. Contradictory findings have been reported from studies that investigated the association between calcium supplementation and hypertension and the risk of stroke and cardiovascular disease. Misinterpretation of findings from studies that are not primarily designed to address these issues might overshadow the benefits of dietary calcium. Until well-designed studies address the current uncertainties, the possible detrimental effect (e.g., hypercalcemia and its complications) of higher-than-recommended calcium intake should be balanced against the likely benefits of calcium on bone, particularly in elderly women.
Calcium supplementation for people with overweight or obesity.
Cormick G, Ciapponi A, Harbron J, Perez S, Vazquez P, Rivo J Cochrane Database Syst Rev. 2024; 5:CD012268.
PMID: 38721870 PMC: 11079972. DOI: 10.1002/14651858.CD012268.pub2.
Vatanparast H, Lane G, Islam N, Patil R, Shafiee M, Whiting S Nutrients. 2023; 15(24).
PMID: 38140325 PMC: 10745417. DOI: 10.3390/nu15245066.
Calcium supplementation for prevention of primary hypertension.
Cormick G, Ciapponi A, Cafferata M, Cormick M, Belizan J Cochrane Database Syst Rev. 2022; 1:CD010037.
PMID: 35014026 PMC: 8748265. DOI: 10.1002/14651858.CD010037.pub4.
Calcium supplementation for prevention of primary hypertension.
Cormick G, Ciapponi A, Cafferata M, Cormick M, Belizan J Cochrane Database Syst Rev. 2021; 8:CD010037.
PMID: 34693985 PMC: 8543682. DOI: 10.1002/14651858.CD010037.pub3.
When Oxidative Stress Meets Epigenetics: Implications in Cancer Development.
Garcia-Guede A, Vera O, Ibanez-de-Caceres I Antioxidants (Basel). 2020; 9(6).
PMID: 32492865 PMC: 7346131. DOI: 10.3390/antiox9060468.