Whole-body Imaging at 7T: Preliminary Results

Overview

Journal Magn Reson Med

Publisher Wiley

Specialty Radiology

Date 2008 Dec 20

PMID 19097214

Citations 109

Authors

J Thomas Vaughan

Carl J Snyder

Lance J Delabarre

Patrick J Bolan

Jinfeng Tian

Lizann Bolinger

Gregor Adriany

Peter Andersen

John Strupp

Kamil Ugurbil

Affiliations

Soon will be listed here.

Abstract

The objective of this study was to investigate the feasibility of whole-body imaging at 7T. To achieve this objective, new technology and methods were developed. Radio frequency (RF) field distribution and specific absorption rate (SAR) were first explored through numerical modeling. A body coil was then designed and built. Multichannel transmit and receive coils were also developed and implemented. With this new technology in hand, an imaging survey of the "landscape" of the human body at 7T was conducted. Cardiac imaging at 7T appeared to be possible. The potential for breast imaging and spectroscopy was demonstrated. Preliminary results of the first human body imaging at 7T suggest both promise and directions for further development.

Citing Articles

Radiomic Machine Learning in Invasive Ductal Breast Cancer: Prediction of Ki-67 Expression Level Based on Radiomics of DCE-MRI.

Yang H, Wang W, Cheng Z, Zheng T, Cheng C, Cheng M Technol Cancer Res Treat. 2024; 23:15330338241288751.

PMID: 39431304 PMC: 11504335. DOI: 10.1177/15330338241288751.

An 8Tx/32Rx head-neck coil at 7T by combining 2Tx/32Rx Nova coil with 6Tx shielded coaxial cable elements.

Guler S, Povaz An M, Zhurbenko V, Zivkovic I Magn Reson Med. 2024; 93(2):864-872.

PMID: 39415491 PMC: 11604854. DOI: 10.1002/mrm.30297.

AC Loss Measurement in NbSn Coil for a New Fast Switching-field MR Concept Magnet.

Kim J, Dong F, Kim J, Bascunan J, Iwasa Y, Ackerman J IEEE Trans Appl Supercond. 2024; 34(5).

PMID: 39386117 PMC: 11460719. DOI: 10.1109/tasc.2024.3360024.

The feasibility of half-dose contrast-enhanced scanning of brain tumours at 5.0 T: a preliminary study.

Jiang Z, Sun W, Xu D, Mei H, Yuan J, Song X BMC Med Imaging. 2024; 24(1):88.

PMID: 38615005 PMC: 11016225. DOI: 10.1186/s12880-024-01270-z.

From strength to precision: A systematic review exploring the clinical utility of 7-Tesla magnetic resonance imaging in abdominal imaging.

Perera Molligoda Arachchige A, Teixeira de Castro Goncalves Ortega A, Catapano F, Politi L, Hoff M World J Radiol. 2024; 16(1):20-31.

PMID: 38312348 PMC: 10835428. DOI: 10.4329/wjr.v16.i1.20.

References

Yacoub E, Van de Moortele P, Shmuel A, Ugurbil K . Signal and noise characteristics of Hahn SE and GE BOLD fMRI at 7 T in humans. Neuroimage. 2005; 24(3):738-50. DOI: 10.1016/j.neuroimage.2004.09.002. View

Metzger G, Snyder C, Akgun C, Vaughan T, Ugurbil K, Van de Moortele P . Local B1+ shimming for prostate imaging with transceiver arrays at 7T based on subject-dependent transmit phase measurements. Magn Reson Med. 2008; 59(2):396-409. PMC: 4406352. DOI: 10.1002/mrm.21476. View

Haddadin I, McIntosh A, Meisamy S, Corum C, Styczynski Snyder A, Powell N . Metabolite quantification and high-field MRS in breast cancer. NMR Biomed. 2007; 22(1):65-76. PMC: 2628417. DOI: 10.1002/nbm.1217. View

Adriany G, Van de Moortele P, Wiesinger F, Moeller S, Strupp J, Andersen P . Transmit and receive transmission line arrays for 7 Tesla parallel imaging. Magn Reson Med. 2005; 53(2):434-45. DOI: 10.1002/mrm.20321. View

Li T, van Gelderen P, Merkle H, Talagala L, Koretsky A, Duyn J . Extensive heterogeneity in white matter intensity in high-resolution T2*-weighted MRI of the human brain at 7.0 T. Neuroimage. 2006; 32(3):1032-40. DOI: 10.1016/j.neuroimage.2006.05.053. View

Vaughan T, DelaBarre L, Snyder C, Tian J, Akgun C, Shrivastava D . 9.4T human MRI: preliminary results. Magn Reson Med. 2006; 56(6):1274-82. PMC: 4406343. DOI: 10.1002/mrm.21073. View

Yacoub E, Shmuel A, Pfeuffer J, Van de Moortele P, Adriany G, Andersen P . Imaging brain function in humans at 7 Tesla. Magn Reson Med. 2001; 45(4):588-94. DOI: 10.1002/mrm.1080. View

Garwood M, Delabarre L . The return of the frequency sweep: designing adiabatic pulses for contemporary NMR. J Magn Reson. 2001; 153(2):155-77. DOI: 10.1006/jmre.2001.2340. View

Qiao H, Zhang X, Zhu X, Du F, Chen W . In vivo 31P MRS of human brain at high/ultrahigh fields: a quantitative comparison of NMR detection sensitivity and spectral resolution between 4 T and 7 T. Magn Reson Imaging. 2006; 24(10):1281-6. PMC: 2610491. DOI: 10.1016/j.mri.2006.08.002. View

10.

Moeller S, Van de Moortele P, Goerke U, Adriany G, Ugurbil K . Application of parallel imaging to fMRI at 7 Tesla utilizing a high 1D reduction factor. Magn Reson Med. 2006; 56(1):118-29. DOI: 10.1002/mrm.20934. View

11.

Van de Moortele P, Akgun C, Adriany G, Moeller S, Ritter J, Collins C . B(1) destructive interferences and spatial phase patterns at 7 T with a head transceiver array coil. Magn Reson Med. 2005; 54(6):1503-18. DOI: 10.1002/mrm.20708. View

12.

Vaughan J, Adriany G, Snyder C, Tian J, Thiel T, Bolinger L . Efficient high-frequency body coil for high-field MRI. Magn Reson Med. 2004; 52(4):851-9. DOI: 10.1002/mrm.20177. View

13.

Wiesinger F, Van de Moortele P, Adriany G, De Zanche N, Ugurbil K, Pruessmann K . Parallel imaging performance as a function of field strength--an experimental investigation using electrodynamic scaling. Magn Reson Med. 2004; 52(5):953-64. DOI: 10.1002/mrm.20281. View

14.

Mangia S, Tkac I, Gruetter R, Van de Moortele P, Giove F, Maraviglia B . Sensitivity of single-voxel 1H-MRS in investigating the metabolism of the activated human visual cortex at 7 T. Magn Reson Imaging. 2006; 24(4):343-8. DOI: 10.1016/j.mri.2005.12.023. View

15.

Vaughan J, Hetherington H, Otu J, Pan J, Pohost G . High frequency volume coils for clinical NMR imaging and spectroscopy. Magn Reson Med. 1994; 32(2):206-18. DOI: 10.1002/mrm.1910320209. View

16.

Vaughan J, Garwood M, Collins C, Liu W, Delabarre L, Adriany G . 7T vs. 4T: RF power, homogeneity, and signal-to-noise comparison in head images. Magn Reson Med. 2001; 46(1):24-30. DOI: 10.1002/mrm.1156. View