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One Gram of Aspirin Per Day Does Not Reduce Risk of Hospitalization for Gallstone Disease

Overview
Journal Dig Dis Sci
Specialty Gastroenterology
Date 1991 Aug 1
PMID 1864205
Citations 5
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Abstract

Data from 4524 patients in a randomized, controlled trial of aspirin were analyzed to determine if aspirin reduced the risk for hospitalization for gallstone disease. Aspirin at a dose of 1000 mg/day did not reduce the risk of hospitalization for gallstones. Hospitalization rates for gallstone disease were consistent with national rates, and the data confirmed previous associations of gallstone disease with age, elevated serum triglycerides, obesity, and female gender.

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References
1.
Goldman G, Kahn P, Alon R, WIZNITZER T . Biliary colic treatment and acute cholecystitis prevention by prostaglandin inhibitor. Dig Dis Sci. 1989; 34(6):809-11. DOI: 10.1007/BF01540262. View

2.
Friedman G, Kannel W, DAWBER T . The epidemiology of gallbladder disease: observations in the Framingham Study. J Chronic Dis. 1966; 19(3):273-92. DOI: 10.1016/0021-9681(66)90132-9. View

3.
Laakso M, Suhonen M, Julkunen R, Pyorala K . Plasma insulin, serum lipids and lipoproteins in gall stone disease in non-insulin dependent diabetic subjects: a case control study. Gut. 1990; 31(3):344-7. PMC: 1378281. DOI: 10.1136/gut.31.3.344. View

4.
Scragg R, McMichael A, Baghurst P . Diet, alcohol, and relative weight in gall stone disease: a case-control study. Br Med J (Clin Res Ed). 1984; 288(6424):1113-9. PMC: 1441375. DOI: 10.1136/bmj.288.6424.1113. View

5.
. The epidemiology of gallstone disease in Rome, Italy. Part II. Factors associated with the disease. The Rome Group for Epidemiology and Prevention of Cholelithiasis (GREPCO). Hepatology. 1988; 8(4):907-13. View