One Gram of Aspirin Per Day Does Not Reduce Risk of Hospitalization for Gallstone Disease
Overview
Authors
Affiliations
Data from 4524 patients in a randomized, controlled trial of aspirin were analyzed to determine if aspirin reduced the risk for hospitalization for gallstone disease. Aspirin at a dose of 1000 mg/day did not reduce the risk of hospitalization for gallstones. Hospitalization rates for gallstone disease were consistent with national rates, and the data confirmed previous associations of gallstone disease with age, elevated serum triglycerides, obesity, and female gender.
The inflammatory inception of gallbladder cancer.
Espinoza J, Bizama C, Garcia P, Ferreccio C, Javle M, Miquel J Biochim Biophys Acta. 2016; 1865(2):245-54.
PMID: 26980625 PMC: 6287912. DOI: 10.1016/j.bbcan.2016.03.004.
Body mass index, abdominal fatness and the risk of gallbladder disease.
Aune D, Norat T, Vatten L Eur J Epidemiol. 2015; 30(9):1009-19.
PMID: 26374741 DOI: 10.1007/s10654-015-0081-y.
Roles of infection, inflammation, and the immune system in cholesterol gallstone formation.
Maurer K, Carey M, Fox J Gastroenterology. 2008; 136(2):425-40.
PMID: 19109959 PMC: 2774219. DOI: 10.1053/j.gastro.2008.12.031.
Cholelithiasic disease and associated factors in a Spanish population.
Devesa F, Ferrando J, Caldentey M, Borghol A, Moreno M, Nolasco A Dig Dis Sci. 2001; 46(7):1424-36.
PMID: 11478494 DOI: 10.1023/a:1010631619162.
Effect of NSAIDs on gallbladder bile composition.
Sterling R, Shiffman M, Sugerman H, Moore E Dig Dis Sci. 1995; 40(10):2220-6.
PMID: 7587793 DOI: 10.1007/BF02209010.