Human Immunodeficiency Virus Type 1 Vpr Links Proteasomal Degradation and Checkpoint Activation

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2007 Sep 15

PMID 17855541

Citations 27

Authors

Jason L DeHart

Vicente Planelles

Affiliations

Soon will be listed here.

Citing Articles

Vpr driving DNA methylation variation of CD4 + T cells in HIV-1 infection.

Wang P, Meng Z, Deng K, Gao Z, Cai J Virol J. 2024; 21(1):97.

PMID: 38671522 PMC: 11046818. DOI: 10.1186/s12985-024-02363-5.

Vpr counteracts the restriction of LAPTM5 to promote HIV-1 infection in macrophages.

Zhao L, Wang S, Xu M, He Y, Zhang X, Xiong Y Nat Commun. 2021; 12(1):3691.

PMID: 34140527 PMC: 8211709. DOI: 10.1038/s41467-021-24087-8.

The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr.

Dupont L, Bloor S, Williamson J, Martinez Cuesta S, Shah R, Teixeira-Silva A Cell Host Microbe. 2021; 29(5):792-805.e6.

PMID: 33811831 PMC: 8118623. DOI: 10.1016/j.chom.2021.03.001.

ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responses.

Bruce J, Bracken M, Evans E, Sherer N, Ahlquist P PLoS Pathog. 2021; 17(2):e1009364.

PMID: 33635925 PMC: 7946322. DOI: 10.1371/journal.ppat.1009364.

Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection.

Greenwood E, Williamson J, Sienkiewicz A, Naamati A, Matheson N, Lehner P Cell Rep. 2019; 27(5):1579-1596.e7.

PMID: 31042482 PMC: 6506760. DOI: 10.1016/j.celrep.2019.04.025.

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