The DAVID Gene Functional Classification Tool: a Novel Biological Module-centric Algorithm to Functionally Analyze Large Gene Lists

Overview

Journal Genome Biol

Specialties Biology
Genetics

Date 2007 Sep 6

PMID 17784955

Citations 1313

Authors

Da Wei Huang

Brad T Sherman

Qina Tan

Jack R Collins

W Gregory Alvord

Jean Roayaei

Robert Stephens

Michael W Baseler

H Clifford Lane

Richard A Lempicki

Affiliations

Soon will be listed here.

Abstract

The DAVID Gene Functional Classification Tool http://david.abcc.ncifcrf.gov uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context.

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