Repolarization Gradients and Arrhythmogenicity in the Murine Heart

Overview

Journal J Physiol

Specialty Physiology

Date 2007 Jul 14

PMID 17627980

Citations 4

Authors

Matthew J Killeen

Ian N Sabir

Affiliations

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Citing Articles

Validation of Noninvasive Epicardial and Endocardial Repolarization Mapping.

Van der Waal J, Meijborg V, Belterman C, Streekstra G, Oostendorp T, Coronel R Front Physiol. 2021; 12:737609.

PMID: 34744778 PMC: 8569864. DOI: 10.3389/fphys.2021.737609.

Murine Electrophysiological Models of Cardiac Arrhythmogenesis.

Huang C Physiol Rev. 2016; 97(1):283-409.

PMID: 27974512 PMC: 5539373. DOI: 10.1152/physrev.00007.2016.

Arrhythmia phenotype in mouse models of human long QT.

Salama G, Baker L, Wolk R, Barhanin J, London B J Interv Card Electrophysiol. 2009; 24(2):77-87.

PMID: 19148726 DOI: 10.1007/s10840-008-9339-6.

Pharmacological separation of early afterdepolarizations from arrhythmogenic substrate in DeltaKPQ Scn5a murine hearts modelling human long QT 3 syndrome.

Thomas G, Killeen M, Grace A, Huang C Acta Physiol (Oxf). 2007; 192(4):505-17.

PMID: 17973950 PMC: 2268972. DOI: 10.1111/j.1748-1716.2007.01770.x.

References

Sabir I, Fraser J, Killeen M, Grace A, Huang C . The contribution of refractoriness to arrhythmic substrate in hypokalemic Langendorff-perfused murine hearts. Pflugers Arch. 2007; 454(2):209-22. PMC: 1839769. DOI: 10.1007/s00424-007-0217-3. View

Shimizu W, Antzelevitch C . Cellular basis for long QT, transmural dispersion of repolarization, and torsade de pointes in the long QT syndrome. J Electrocardiol. 2000; 32 Suppl:177-84. DOI: 10.1016/s0022-0736(99)90077-8. View

London B . Cardiac arrhythmias: from (transgenic) mice to men. J Cardiovasc Electrophysiol. 2001; 12(9):1089-91. DOI: 10.1046/j.1540-8167.2001.01089.x. View

Papadatos G, Wallerstein P, Head C, Ratcliff R, Brady P, Benndorf K . Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci U S A. 2002; 99(9):6210-5. PMC: 122928. DOI: 10.1073/pnas.082121299. View

London B, Baker L, Petkova-Kirova P, Nerbonne J, Choi B, Salama G . Dispersion of repolarization and refractoriness are determinants of arrhythmia phenotype in transgenic mice with long QT. J Physiol. 2006; 578(Pt 1):115-29. PMC: 2075135. DOI: 10.1113/jphysiol.2006.122622. View