» Articles » PMID: 17615057

FlyMine: an Integrated Database for Drosophila and Anopheles Genomics

Abstract

FlyMine is a data warehouse that addresses one of the important challenges of modern biology: how to integrate and make use of the diversity and volume of current biological data. Its main focus is genomic and proteomics data for Drosophila and other insects. It provides web access to integrated data at a number of different levels, from simple browsing to construction of complex queries, which can be executed on either single items or lists.

Citing Articles

A curated tissue-specific proteome, phosphoproteome, and kinome map of Drosophila melanogaster with an integrated outlook in circadian physiology.

Das S, Kannihalli A, Banerjee S, Chakraborty N, Ray S Funct Integr Genomics. 2025; 25(1):41.

PMID: 39971807 DOI: 10.1007/s10142-025-01554-9.


Genomics of a sexually selected sperm ornament and female preference in Drosophila.

Syed Z, Gomez R, Borziak K, Asif A, Cong A, OGrady P Nat Ecol Evol. 2024; 9(2):336-348.

PMID: 39578595 DOI: 10.1038/s41559-024-02587-2.


A naturally occurring mitochondrial genome variant confers broad protection from infection in Drosophila.

Salminen T, Vesala L, Basikhina Y, Kutzer M, Tuomela T, Lucas R PLoS Genet. 2024; 20(11):e1011476.

PMID: 39527645 PMC: 11614270. DOI: 10.1371/journal.pgen.1011476.


Egg multivesicular bodies elicit an LC3-associated phagocytosis-like pathway to degrade paternal mitochondria after fertilization.

Ben-Hur S, Sernik S, Afar S, Kolpakova A, Politi Y, Gal L Nat Commun. 2024; 15(1):5715.

PMID: 38977659 PMC: 11231261. DOI: 10.1038/s41467-024-50041-5.


The endosymbiont increases resistance to pathogens by enhancing iron sequestration and melanization.

Hrdina A, Serra Canales M, Arias-Rojas A, Frahm D, Iatsenko I mBio. 2024; 15(8):e0093624.

PMID: 38940615 PMC: 11323552. DOI: 10.1128/mbio.00936-24.


References
1.
Simmer F, Moorman C, van der Linden A, Kuijk E, van den Berghe P, Kamath R . Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol. 2003; 1(1):E12. PMC: 212692. DOI: 10.1371/journal.pbio.0000012. View

2.
Philips J, Rubin E, Perrimon N . Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection. Science. 2005; 309(5738):1251-3. DOI: 10.1126/science.1116006. View

3.
Bergman C, Carlson J, Celniker S . Drosophila DNase I footprint database: a systematic genome annotation of transcription factor binding sites in the fruitfly, Drosophila melanogaster. Bioinformatics. 2004; 21(8):1747-9. DOI: 10.1093/bioinformatics/bti173. View

4.
Walhout A, Reboul J, Shtanko O, Bertin N, Vaglio P, Ge H . Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline. Curr Biol. 2002; 12(22):1952-8. DOI: 10.1016/s0960-9822(02)01279-4. View

5.
Rhodes D, Tomlins S, Varambally S, Mahavisno V, Barrette T, Kalyana-Sundaram S . Probabilistic model of the human protein-protein interaction network. Nat Biotechnol. 2005; 23(8):951-9. DOI: 10.1038/nbt1103. View