Brooke-Spiegler Syndrome - Report of Four Families: Treatment with CO2 Laser
Overview
Affiliations
Background: Brooke-Spiegler syndrome is a well known but rare cutaneous disorder characterized by the presence of multiple trichoepitheliomas and cylindromas.
Methods: Four families with Brooke-Spiegler syndrome are described.
Results: Spiradenomas developed on the back in two patients. A CO(2) laser was used to treat facial trichoepitheliomas in two patients with good results.
Conclusions: The large number of facial lesions in this syndrome often produce a significant emotional impact. We believe that it is important to provide patients with a good therapeutic option. CO(2) laser therapy may fill this role.
Bonadies A, Iorio A, Silipo V, Cota C, Govoni F, Battista M Biomedicines. 2023; 11(10).
PMID: 37893041 PMC: 10604352. DOI: 10.3390/biomedicines11102667.
Plachta I, Kleibert M, Czarnecka A, Spalek M, Szumera-Cieckiewicz A, Rutkowski P Int J Mol Sci. 2021; 22(10).
PMID: 34064849 PMC: 8151110. DOI: 10.3390/ijms22105077.
Rostami Mogaddam M, Maleki N J Res Med Sci. 2016; 20(9):923-4.
PMID: 26759583 PMC: 4696381. DOI: 10.4103/1735-1995.170638.
Benign cylindroma: a rare differential diagnosis of external ear canal tumour.
Schwarz D, Drebber U, Ortmann M, Anagiotos A BMJ Case Rep. 2016; 2016.
PMID: 26759396 PMC: 4716316. DOI: 10.1136/bcr-2015-212035.
Basal Cell Adenoma of the Parotid Gland-A Rare Entity.
Rajasenthil V, Ravi A Indian J Surg. 2015; 76(5):408-10.
PMID: 26396476 PMC: 4571517. DOI: 10.1007/s12262-013-1010-5.