Lipid Rafts and Membrane Traffic

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 2007 Mar 27

PMID 17382322

Citations 114

Authors

Michael F Hanzal-Bayer

John F Hancock

Affiliations

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Abstract

Membrane rafts are regions of increased lipid acyl chain order that differ in their lipid and protein composition from the surrounding membrane. By providing an additional level of compartmentalization they have been proposed to serve many functions in cellular signal transduction and trafficking. We will review their potential involvement in different forms of membrane traffic, explicitly excluding signalling, and discuss select aspects of the raft hypothesis in its current form.

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