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Cellular Senescence and Chromatin Organisation

Overview
Journal Br J Cancer
Specialty Oncology
Date 2007 Feb 22
PMID 17311013
Citations 33
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Abstract

Despite the potential importance of senescence in tumour suppression, its effector mechanism is poorly understood. Recent studies suggest that alterations in the chromatin environment might add an additional layer of stability to the phenotype. In this review, recent discoveries on the interplay between senescence and chromatin biology are overviewed.

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