Computational Methods for Analysis of Human Breast Tumor Tissue in Optical Coherence Tomography Images

Overview

Journal J Biomed Opt

Specialties Biomedical Engineering
Ophthalmology

Date 2006 Nov 10

PMID 17092164

Citations 40

Authors

Adam M Zysk

Stephen A Boppart

Affiliations

Soon will be listed here.

Abstract

Optical coherence tomography (OCT) has been demonstrated as a promising means of identifying the boundaries between normal and diseased breast tissue. This capability has yielded promise for the development of OCT techniques for biopsy guidance, surgical margin assessment, and minimally invasive evaluation of disease states. We present methods for the assessment of human breast tissue based on spatial and Fourier-domain analysis. Derived from preliminary OCT data, these methods are aimed at the development of automated diagnostic tools that will aid in the translation of this technology into the clinical environment.

Citing Articles

Robust High-Resolution Fine OCT Needle for Side-Viewing Interstitial Tissue Imaging.

Wu Y, Xi J, Huo L, Padvorac J, Shin E, Giday S IEEE J Sel Top Quantum Electron. 2024; 16(4):863-869.

PMID: 39734745 PMC: 11675607. DOI: 10.1109/jstqe.2009.2035362.

Multimodal Raman spectroscopy and optical coherence tomography for biomedical analysis.

Fitzgerald S, Akhtar J, Schartner E, Ebendorff-Heidepriem H, Mahadevan-Jansen A, Li J J Biophotonics. 2022; 16(3):e202200231.

PMID: 36308009 PMC: 10082563. DOI: 10.1002/jbio.202200231.

Characterization and quantification of necrotic tissues and morphology in multicellular ovarian cancer tumor spheroids using optical coherence tomography.

Yan F, Gunay G, Valerio T, Wang C, Wilson J, Haddad M Biomed Opt Express. 2021; 12(6):3352-3371.

PMID: 34221665 PMC: 8221959. DOI: 10.1364/BOE.425512.

Differentiation of breast tissue types for surgical margin assessment using machine learning and polarization-sensitive optical coherence tomography.

Zhu D, Wang J, Marjanovic M, Chaney E, Cradock K, Higham A Biomed Opt Express. 2021; 12(5):3021-3036.

PMID: 34168912 PMC: 8194620. DOI: 10.1364/BOE.423026.

Diagnostic Accuracy of Cross-Polarization OCT and OCT-Elastography for Differentiation of Breast Cancer Subtypes: Comparative Study.

Gubarkova E, Kiseleva E, Sirotkina M, Vorontsov D, Achkasova K, Kuznetsov S Diagnostics (Basel). 2020; 10(12).

PMID: 33255263 PMC: 7760404. DOI: 10.3390/diagnostics10120994.