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Stephen A Boppart

Explore the profile of Stephen A Boppart including associated specialties, affiliations and a list of published articles. Areas
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Articles 350
Citations 5718
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Recent Articles
1.
De la Cadena A, Renteria C, Aksamitiene E, Boppart S
Opt Lett . 2025 Feb; 50(5):1484-1487. PMID: 40019961
Label-free multiphoton microscopy is a powerful tool for investigating pristine biological specimens. This imaging modality leverages optical signals originating from the nonlinear response of native biomolecules to intense optical radiation,...
2.
Shi J, Ho A, Snyder C, Chaney E, Sorrells J, Alex A, et al.
Commun Biol . 2025 Feb; 8(1):157. PMID: 39900674
The selection of high-performing cell lines is crucial for biopharmaceutical production but is often time-consuming and labor-intensive. We investigated label-free multimodal nonlinear optical microscopy for non-perturbative profiling of biopharmaceutical cell...
3.
Wang G, Iyer R, Sorrells J, Aksamitiene E, Chaney E, Renteria C, et al.
Laser Photon Rev . 2025 Jan; 18(10. PMID: 39781104
Irreproducibility in molecular optical sectioning microscopy has hindered the transformation of acquired digital images from qualitative descriptions to quantitative data. Although numerous tools, metrics, and phantoms have been developed, accurate...
4.
Szulczewski J, Yesilkoy F, Ulland T, Bartels R, Millis B, Boppart S, et al.
J Biomed Opt . 2024 Dec; 29(Suppl 2):S22717. PMID: 39711795
Significance: Advances in label-free imaging have impacted many areas of biological and biomedical imaging ranging from cell biology and cancer to pathology and neuroscience. Despite the great progress and advantages...
5.
Boppart S, Best-Popescu C, Bartels R, Eliceiri K
J Biomed Opt . 2024 Dec; 29(Suppl 2):S22701. PMID: 39703751
The editorial introduces the JBO special issue honoring Prof. Gabriel Popescu, Pioneer in Biomedical Optics.
6.
Das Gupta A, Park J, Sorrells J, Kim H, Krawczynska N, Pradeep D, et al.
Endocrinology . 2024 Sep; 165(11). PMID: 39298675
Extracellular vesicles (EVs) serve as crucial mediators of cell-to-cell communication in normal physiology as well as in diseased states; they have been largely studied in regard to their role in...
7.
Majer J, Alex A, Shi J, Chaney E, Mukherjee P, Spillman Jr D, et al.
Lab Chip . 2024 Sep; 24(19):4594-4608. PMID: 39258913
A liver-on-a-chip model is an advanced complex model (CIVM) that incorporates different cell types and extracellular matrix to mimic the microenvironment of the human liver in a laboratory setting. Given...
8.
Zaki F, Monroy G, Shi J, Sudhir K, Boppart S
J Biophotonics . 2024 Aug; 17(10):e202400075. PMID: 39103198
Otitis media (OM), a highly prevalent inflammatory middle-ear disease in children worldwide, is commonly caused by an infection, and can lead to antibiotic-resistant bacterial biofilms in recurrent/chronic OM cases. A...
9.
Roh T, Alex A, Chandramouleeswaran P, Sorrells J, Ho A, Iyer R, et al.
Redox Biol . 2024 Jul; 75:103280. PMID: 39083897
The DNA damage response (DDR) is a fundamental readout for evaluating efficacy of cancer therapeutics, many of which target DNA associated processes. Current techniques to evaluate DDR rely on immunostaining...
10.
Iyer R, Yang L, Sorrells J, Chaney E, Spillman Jr D, Boppart S
APL Photonics . 2024 Jul; 9(7):076114. PMID: 39072189
The applications of ultrafast optics to biomedical microscopy have expanded rapidly in recent years, including interferometric techniques like optical coherence tomography and microscopy (OCT/OCM). The advances of ultra-high resolution OCT...