Metabolic Cycle, Cell Cycle, and the Finishing Kick to Start

Overview

Journal Genome Biol

Specialties Biology
Genetics

Date 2006 May 9

PMID 16677426

Citations 39

Authors

Bruce Futcher

Affiliations

Soon will be listed here.

Abstract

Slowly growing budding yeast store carbohydrate, then liquidate it in late G1 phase of the cell cycle, superimposing a metabolic cycle on the cell cycle. This metabolic cycle may separate biochemically incompatible processes. Alternatively it may provide a burst of energy and material for commitment to the cell cycle. Stored carbohydrate could explain the size requirement for cells passing the Start point.

Citing Articles

Evaluating cellular roles and phenotypes associated with trehalose degradation genes in Saccharomyces cerevisiae.

Chen A, Stadulis S, deLeuze K, Gibney P G3 (Bethesda). 2024; 14(11).

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PKA regulatory subunit Bcy1 couples growth, lipid metabolism, and fermentation during anaerobic xylose growth in Saccharomyces cerevisiae.

Wagner E, Nightingale N, Jen A, Overmyer K, McGee M, Coon J PLoS Genet. 2023; 19(7):e1010593.

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Using the AKAR3-EV biosensor to assess Sch9p- and PKA-signalling in budding yeast.

Botman D, Kanagasabapathi S, Savakis P, Teusink B FEMS Yeast Res. 2023; 23.

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Temporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle.

Takhaveev V, Ozsezen S, Smith E, Zylstra A, Chaillet M, Chen H Nat Metab. 2023; 5(2):294-313.

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Bend or break: how biochemically versatile molecules enable metabolic division of labor in clonal microbial communities.

Varahan S, Laxman S Genetics. 2021; 219(2).

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