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Role of DNA Replication in the Repression of Silent Mating Type Loci in Yeast

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Journal Nature
Specialty Science
Date 1984 Nov 15
PMID 6390211
Citations 102
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Abstract

A putative origin of DNA replication is associated with the DNA sequences necessary for the repression of silent mating type loci in yeast. These sequences lie about a kilobase away from the affected promoters, so the repression must act at a distance. We show here that DNA replication is required for the onset of repression.

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