Beyond Mfold: Recent Advances in RNA Bioinformatics

Overview

Journal J Biotechnol

Specialties Biomedical Engineering
Biotechnology

Date 2006 Mar 15

PMID 16530285

Citations 34

Authors

Jens Reeder

Matthias Hochsmann

Marc Rehmsmeier

Bjorn Voss

Robert Giegerich

Affiliations

Soon will be listed here.

Abstract

Computational analysis of RNA secondary structure is a classical field of biosequence analysis, which has recently gained momentum due to the manyfold regulatory functions of RNA that have become apparent. We present five recent computational approaches that address the problems of synoptic folding space analysis, pseudoknot prediction, structure alignment, comparative structure prediction, and miRNA target prediction. All these programs are in current use and are available via the Bielefeld Bioinformatics Server at .

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