The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30): Validation Study of the Thai Version

Overview

Journal Qual Life Res

Specialties Pharmacology
Rehabilitation Medicine

Date 2006 Jan 18

PMID 16411041

Citations 19

Authors

Chatchawan Silpakit

Suwanee Sirilerttrakul

Manmana Jirajarus

Thitiya Sirisinha

Ekaphop Sirachainan

Vorachai Ratanatharathorn

Affiliations

Soon will be listed here.

Abstract

The objective of this study was to assess the psychometric properties of the Thai version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) version 3.0. The questionnaire was completed by 310 cancer patients during their follow-up at 2 teaching hospital oncology clinics. About 70% of participants had advanced stage of cancer and 72% had been receiving chemotherapy. Cronbach's alpha coefficients of the six scales were above 0.7, except for cognitive and social function scales. All test-retest reliability coefficients were high. Multi trait scaling analysis showed that all item-scale correlation coefficients met the standards of convergent and discriminant validity. Most scales and items could discriminate between subgroups of patients with different clinical status assessed with the Eastern Cooperative Oncology Group (ECOG) scale. The results suggested that the EORTC QLQ-C30 and the Functional Assessment of Cancer Therapy - General (FACT-G) measured different aspects of quality of life and should be independently used. Testing psychometric properties of the EORTC QLQ-C30 in heterogeneous diagnostic group yield similar results as found in homogeneous group. These results support that the EORTC QLQ-C30 (version 3.0) has proven to be a reliable and valid measure of the quality of life in Thai patients with various types of cancer.

Citing Articles

Developing a Card Game for Assessment and Intervention in the Person and the Family in Palliative Care: "".

Fernandes C, Vale M, Magalhaes B, Castro J, Azevedo M, Lourenco M Int J Environ Res Public Health. 2023; 20(2).

PMID: 36674205 PMC: 9859236. DOI: 10.3390/ijerph20021449.

Validation of Gujarati Version of European Organization for Research and Treatment of Cancer Quality of Life Modules in Head and Neck Cancer Patients of Western India.

Parkar S, Sharma A, Shah M Indian J Otolaryngol Head Neck Surg. 2022; 74(Suppl 2):2291-2301.

PMID: 36452740 PMC: 9702444. DOI: 10.1007/s12070-020-02126-y.

Psychometric properties of the Spanish version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30).

Calderon C, Ferrando P, Lorenzo-Seva U, Ferreira E, Lee E, Oporto-Alonso M Qual Life Res. 2021; 31(6):1859-1869.

PMID: 34928470 PMC: 9098585. DOI: 10.1007/s11136-021-03068-w.

The prevalence of depressive disorder and its association in Thai cervical cancer patients.

Karawekpanyawong N, Kaewkitikul K, Maneeton B, Maneeton N, Siriaree S PLoS One. 2021; 16(6):e0252779.

PMID: 34153051 PMC: 8216533. DOI: 10.1371/journal.pone.0252779.

Temporal stability of quality of life assessments in cancer patients.

Hinz A, Schulte T, Rassler J, Zenger M, Geue K Sci Rep. 2021; 11(1):5191.

PMID: 33664409 PMC: 7933346. DOI: 10.1038/s41598-021-84681-0.

References

Thongprasert S . Lung cancer and quality of life. Aust N Z J Med. 1998; 28(3):397-9. DOI: 10.1111/j.1445-5994.1998.tb01973.x. View

Hjermstad M, Fossa S, Bjordal K, Kaasa S . Test/retest study of the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire. J Clin Oncol. 1995; 13(5):1249-54. DOI: 10.1200/JCO.1995.13.5.1249. View

Schipper H, Clinch J, McMurray A, Levitt M . Measuring the quality of life of cancer patients: the Functional Living Index-Cancer: development and validation. J Clin Oncol. 1984; 2(5):472-83. DOI: 10.1200/JCO.1984.2.5.472. View

Kobayashi K, Takeda F, Teramukai S, Gotoh I, Sakai H, Yoneda S . A cross-validation of the European Organization for Research and Treatment of Cancer QLQ-C30 (EORTC QLQ-C30) for Japanese with lung cancer. Eur J Cancer. 1998; 34(6):810-5. DOI: 10.1016/s0959-8049(97)00395-x. View

Zhao H, Kanda K . Testing psychometric properties of the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30). J Epidemiol. 2004; 14(6):193-203. PMC: 8784239. DOI: 10.2188/jea.14.193. View

Holzner B, Kemmler G, Sperner-Unterweger B, Kopp M, Dunser M, Margreiter R . Quality of life measurement in oncology--a matter of the assessment instrument?. Eur J Cancer. 2001; 37(18):2349-56. DOI: 10.1016/s0959-8049(01)00307-0. View

Aaronson N, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez N . The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993; 85(5):365-76. DOI: 10.1093/jnci/85.5.365. View

Montazeri A, Harirchi I, Vahdani M, Khaleghi F, Jarvandi S, Ebrahimi M . The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30): translation and validation study of the Iranian version. Support Care Cancer. 1999; 7(6):400-6. DOI: 10.1007/s005200050300. View

Chie W, Yang C, Hsu C, Yang P . Quality of life of lung cancer patients: validation of the Taiwan Chinese version of the EORTC QLQ-C30 and QLQ-LC13. Qual Life Res. 2004; 13(1):257-62. DOI: 10.1023/B:QURE.0000015295.74812.06. View

10.

Ferrell B, Dow K, Grant M . Measurement of the quality of life in cancer survivors. Qual Life Res. 1995; 4(6):523-31. DOI: 10.1007/BF00634747. View

11.

Cella D, Tulsky D, Gray G, Sarafian B, Linn E, Bonomi A . The Functional Assessment of Cancer Therapy scale: development and validation of the general measure. J Clin Oncol. 1993; 11(3):570-9. DOI: 10.1200/JCO.1993.11.3.570. View

12.

Ratanatharathorn V, Sirilerttrakul S, Jirajarus M, Silpakit C, Maneechavakajorn J, Sailamai P . Quality of life, Functional Assessment of Cancer Therapy-General. J Med Assoc Thai. 2002; 84(10):1430-42. View

13.

Ringdal G, Ringdal K . Testing the EORTC Quality of Life Questionnaire on cancer patients with heterogeneous diagnoses. Qual Life Res. 1993; 2(2):129-40. DOI: 10.1007/BF00435732. View

14.

Cheung Y, Thumboo J, Goh C, Khoo K, Che W, Wee J . The equivalence and difference between the English and Chinese versions of two major, cancer-specific, health-related quality-of-life questionnaires. Cancer. 2004; 101(12):2874-80. DOI: 10.1002/cncr.20681. View

15.

Kemmler G, Holzner B, Kopp M, Dunser M, Margreiter R, Greil R . Comparison of two quality-of-life instruments for cancer patients: the functional assessment of cancer therapy-general and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30. J Clin Oncol. 1999; 17(9):2932-40. DOI: 10.1200/JCO.1999.17.9.2932. View

16.

Lee S, Earle C, Weeks J . Outcomes research in oncology: history, conceptual framework, and trends in the literature. J Natl Cancer Inst. 2000; 92(3):195-204. DOI: 10.1093/jnci/92.3.195. View

17.

Yun Y, Park Y, Lee E, Bang S, Heo D, Park S . Validation of the Korean version of the EORTC QLQ-C30. Qual Life Res. 2004; 13(4):863-8. DOI: 10.1023/B:QURE.0000021692.81214.70. View

18.

Sirisinha T, Ratanatharathorn V, Jirajarus M, Sirilerttrakul S, Silpakit C, Sirachainan E . The European Organization for Research and Treatment of Cancer quality of life questionnaire: translation and reliability study of the Thai version. J Med Assoc Thai. 2003; 85(11):1210-9. View

19.

Osoba D, Zee B, Pater J, Warr D, Kaizer L, Latreille J . Psychometric properties and responsiveness of the EORTC quality of Life Questionnaire (QLQ-C30) in patients with breast, ovarian and lung cancer. Qual Life Res. 1994; 3(5):353-64. DOI: 10.1007/BF00451727. View