Validation of Gujarati Version of European Organization for Research and Treatment of Cancer Quality of Life Modules in Head and Neck Cancer Patients of Western India

Overview

Journal Indian J Otolaryngol Head Neck Surg

Publisher Springer

Date 2022 Dec 1

PMID 36452740

Authors

Sujal Parkar

Abhishek Sharma

Mihir Shah

Affiliations

Soon will be listed here.

Abstract

Head and neck cancer and its treatment had a significant impact on the quality of life. EORTC QLQ-C30 and EORTC QLQ-H&N35 are the two most widely used modules to assess the quality of life among head and neck cancer patients. The aim of the study is to test the reliability and validity of Gujarati version of EORTC QLQ-C30 and QLQ-H&N35module in a clinical setting. Gujarati version of EORTC QLQ-C30 and QLQ-H&N35 was administered to 400 histo-pathologically proven cases of head and neck cancer. For testing the internal consistency (reliability) Cronbach's alpha coefficient was used. The convergent and discriminant validity were explored by using Spearman's correlation coefficient test. Factor analysis was performed to obtain information about loading of the items for each scale. All most all scales of EORTC QLQ-C30 and QLQ-H&N35 showed high internal consistency having Cronbach's alpha coefficient > 0.70. Spearman's correlation coefficient ranges from -0.45 to 0.95 for EORTC QLQ-C30 and 0.42-0.94 for EORTC QLQ-H&N35 showing moderate to good convergent validity. The magnitude of the correlation of each item with its own scale exceeded the correlation with another scale confirming item discriminant validity. The factor analysis resulted in 7 and 11 different components for measuring quality of life for EORTC QLQ-C30 and QLQ-H&N35 respectively. Based on the results obtained it can be concluded that the Gujarati version of both the modules is a reliable and valid tool for measuring quality of life in head and neck cancer patients in clinical settings.

Citing Articles

Validation of European Organization for Research and Treatment of Cancer Head and Neck Cancer Quality of Life Questionnaire (EORTC QLQ-H&N35) Across Languages: A Systematic Review.

Parkar S, Sharma A Indian J Otolaryngol Head Neck Surg. 2023; 74(Suppl 3):6100-6107.

PMID: 36742587 PMC: 9895643. DOI: 10.1007/s12070-021-02755-x.

References

Carrillo J, Ortiz-Toledo M, Salido-Noriega Z, Romero-Ventura N, Ochoa-Carrillo F, Onate-Ocana L . Validation of the Mexican Spanish version of the EORTC QLQ-H&N35 instrument to measure health-related quality of life in patients with head and neck cancers. Ann Surg Oncol. 2012; 20(5):1417-26. DOI: 10.1245/s10434-012-2712-9. View

Bjordal K, de Graeff A, Fayers P, Hammerlid E, van Pottelsberghe C, Curran D . A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. EORTC Quality of Life Group. Eur J Cancer. 2000; 36(14):1796-807. DOI: 10.1016/s0959-8049(00)00186-6. View

Jham B, Freire A . Oral complications of radiotherapy in the head and neck. Braz J Otorhinolaryngol. 2007; 72(5):704-8. PMC: 9443542. DOI: 10.1016/s1808-8694(15)31029-6. View

Sharma R . Kuppuswamy's socioeconomic status scale--revision for 2011 and formula for real-time updating. Indian J Pediatr. 2012; 79(7):961-2. DOI: 10.1007/s12098-011-0679-3. View

Chaukar D, Das A, Deshpande M, Pai P, Pathak K, Chaturvedi P . Quality of life of head and neck cancer patient: validation of the European organization for research and treatment of cancer QLQ-C30 and European organization for research and treatment of cancer QLQ-H&N 35 in Indian patients. Indian J Cancer. 2006; 42(4):178-84. View

Apolone G, Filiberti A, Cifani S, Ruggiata R, Mosconi P . Evaluation of the EORTC QLQ-C30 questionnaire: a comparison with SF-36 Health Survey in a cohort of Italian long-survival cancer patients. Ann Oncol. 1998; 9(5):549-57. DOI: 10.1023/a:1008264412398. View

Mehanna H, Morton R . Does quality of life predict long-term survival in patients with head and neck cancer?. Arch Otolaryngol Head Neck Surg. 2006; 132(1):27-31. DOI: 10.1001/archotol.132.1.27. View

Andrews N, Griffiths C . Dental complications of head and neck radiotherapy: Part 1. Aust Dent J. 2001; 46(2):88-94. DOI: 10.1111/j.1834-7819.2001.tb00562.x. View

Guzelant A, Goksel T, Ozkok S, Tasbakan S, Aysan T, Bottomley A . The European Organization for Research and Treatment of Cancer QLQ-C30: an examination into the cultural validity and reliability of the Turkish version of the EORTC QLQ-C30. Eur J Cancer Care (Engl). 2004; 13(2):135-44. DOI: 10.1111/j.1365-2354.2003.00435.x. View

10.

Bjordal K, Ahlner-Elmqvist M, Tollesson E, Jensen A, Razavi D, Maher E . Development of a European Organization for Research and Treatment of Cancer (EORTC) questionnaire module to be used in quality of life assessments in head and neck cancer patients. EORTC Quality of Life Study Group. Acta Oncol. 1994; 33(8):879-85. DOI: 10.3109/02841869409098450. View

11.

Davudov M, Rahimov C, Harirchi I, Mirzajani Z, Amiraliyev N, Amiraliyev K . Psychometric evaluation of Azeri version of the head and neck cancer specific quality of life questionnaire (EORTC QLQ-H&N43). Health Qual Life Outcomes. 2020; 18(1):248. PMC: 7379343. DOI: 10.1186/s12955-020-01500-2. View

12.

Sherman A, Simonton S, Adams D, Vural E, Owens B, Hanna E . Assessing quality of life in patients with head and neck cancer: cross-validation of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Head and Neck module (QLQ-H&N35). Arch Otolaryngol Head Neck Surg. 2000; 126(4):459-67. DOI: 10.1001/archotol.126.4.459. View

13.

Nalbadian M, Nikolaidis V, Nikolaou A, Themelis C, Kouloulas A, Vital V . Psychometric properties of the EORTC head and neck-specific quality of life questionnaire in disease-free Greek patients with cancer of pharynx and larynx. Qual Life Res. 2010; 19(5):761-8. DOI: 10.1007/s11136-010-9628-2. View

14.

Gliklich R, Goldsmith T, Funk G . Are head and neck specific quality of life measures necessary?. Head Neck. 1997; 19(6):474-80. DOI: 10.1002/(sici)1097-0347(199709)19:6<474::aid-hed3>3.0.co;2-w. View

15.

DAntonio L, Zimmerman G, Cella D, Long S . Quality of life and functional status measures in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg. 1996; 122(5):482-7. DOI: 10.1001/archotol.1996.01890170018005. View

16.

Aaronson N, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez N . The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993; 85(5):365-76. DOI: 10.1093/jnci/85.5.365. View

17.

Silpakit C, Sirilerttrakul S, Jirajarus M, Sirisinha T, Sirachainan E, Ratanatharathorn V . The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30): validation study of the Thai version. Qual Life Res. 2006; 15(1):167-72. DOI: 10.1007/s11136-005-0449-7. View

18.

Luo N, Fones C, Lim S, Xie F, Thumboo J, Li S . The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-c30): validation of English version in Singapore. Qual Life Res. 2005; 14(4):1181-6. DOI: 10.1007/s11136-004-4782-z. View

19.

Bjordal K, Hammerlid E, Ahlner-Elmqvist M, de Graeff A, Boysen M, Evensen J . Quality of life in head and neck cancer patients: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H&N35. J Clin Oncol. 1999; 17(3):1008-19. DOI: 10.1200/JCO.1999.17.3.1008. View

20.

Lee E, Chun M, Wang H, Lim H, Choi J . Multidimensional constructs of the EORTC Quality of Life Questionnaire (QLQ-c30) in Korean cancer patients with heterogeneous diagnoses. Cancer Res Treat. 2009; 37(3):148-56. PMC: 2785408. DOI: 10.4143/crt.2005.37.3.148. View