One Hundred Years of Research in the Pathogenesis of Pulmonary Hypertension

Overview

Journal Am J Respir Cell Mol Biol

Specialties Cell Biology
Molecular Biology

Date 2005 Oct 20

PMID 16234331

Citations 32

Authors

Ari Zaiman

Iwona Fijalkowska

Paul M Hassoun

Rubin M Tuder

Affiliations

Soon will be listed here.

Citing Articles

The critical roles of caveolin-1 in lung diseases.

Fan J, Zheng S, Wang M, Yuan X Front Pharmacol. 2024; 15:1417834.

PMID: 39380904 PMC: 11458383. DOI: 10.3389/fphar.2024.1417834.

Unilateral Lung Removal in Combination with Monocrotaline or SU5416 in Rodents: A Reliable Model to Mimic the Pathology of the Human Pulmonary Hypertension.

Katz M, Hadas Y, Shtraizent N, Ravvin S, Madjarov J, Eliyahu E Methods Mol Biol. 2024; 2803:173-185.

PMID: 38676893 DOI: 10.1007/978-1-0716-3846-0_13.

Tensions in Taxonomies: Current Understanding and Future Directions in the Pathobiologic Basis and Treatment of Group 1 and Group 3 Pulmonary Hypertension.

Gu S, Goel K, Forbes L, Kheyfets V, Yu Y, Tuder R Compr Physiol. 2023; 13(1):4295-4319.

PMID: 36715285 PMC: 10392122. DOI: 10.1002/cphy.c220010.

A Protocol for Fabrication and on-Chip Cell Culture to Recreate PAH-Afflicted Pulmonary Artery on a Microfluidic Device.

Sarkar T, Nguyen T, Moinuddin S, Stenmark K, Nozik E, Saha D Micromachines (Basel). 2022; 13(9).

PMID: 36144106 PMC: 9504537. DOI: 10.3390/mi13091483.

Single-cell RNA sequencing reveals that mutation regulates right ventricular function genes.

Du M, Jiang H, Liu H, Zhao X, Zhou Y, Zhou F Eur Respir J. 2021; 60(1).

PMID: 34857612 PMC: 9260124. DOI: 10.1183/13993003.00327-2021.

References

Frid M, Aldashev A, Dempsey E, Stenmark K . Smooth muscle cells isolated from discrete compartments of the mature vascular media exhibit unique phenotypes and distinct growth capabilities. Circ Res. 1997; 81(6):940-52. DOI: 10.1161/01.res.81.6.940. View

Morse J, Jones A, Barst R, Hodge S, Wilhelmsen K, Nygaard T . Mapping of familial primary pulmonary hypertension locus (PPH1) to chromosome 2q31-q32. Circulation. 1997; 95(12):2603-6. DOI: 10.1161/01.cir.95.12.2603. View

HYMAN A, Chapnick B, Kadowitz P, Lands W, Crawford C, Fried J . Unusual pulmonary vasodilator activity of 13,14-dehydroprostacyclin methyl ester: comparison with endoperoxides and other prostanoids. Proc Natl Acad Sci U S A. 1977; 74(12):5711-5. PMC: 431863. DOI: 10.1073/pnas.74.12.5711. View

Zhao Y, Courtman D, Deng Y, Kugathasan L, Zhang Q, Stewart D . Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease. Circ Res. 2005; 96(4):442-50. DOI: 10.1161/01.RES.0000157672.70560.7b. View

Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J . Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J. 2001; 15(2):427-38. DOI: 10.1096/fj.00-0343com. View

Christman B, McPherson C, Newman J, King G, Bernard G, GROVES B . An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Engl J Med. 1992; 327(2):70-5. DOI: 10.1056/NEJM199207093270202. View

Gruetter C, Barry B, McNamara D, Gruetter D, Kadowitz P, Ignarro L . Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside and a carcinogenic nitrosoamine. J Cyclic Nucleotide Res. 1979; 5(3):211-24. View

Lee S, Shroyer K, Markham N, Cool C, Voelkel N, Tuder R . Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension. J Clin Invest. 1998; 101(5):927-34. PMC: 508641. DOI: 10.1172/JCI1910. View

Loscalzo J . Endothelial dysfunction in pulmonary hypertension. N Engl J Med. 1992; 327(2):117-9. DOI: 10.1056/NEJM199207093270209. View

10.

Wood P, Besterman E, TOWERS M, McIlroy M . The effect of acetylcholine on pulmonary vascular resistance and left atrial pressure in mitral stenosis. Br Heart J. 1957; 19(2):279-86. PMC: 479626. DOI: 10.1136/hrt.19.2.279. View

11.

Carrillo L, AVIADO D . Monocrotaline-induced pulmonary hypertension and p-chlorophenylalanine (PCPA). Lab Invest. 1969; 20(3):243-8. View

12.

Giaid A, Yanagisawa M, Langleben D, Michel R, Levy R, Shennib H . Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med. 1993; 328(24):1732-9. DOI: 10.1056/NEJM199306173282402. View

13.

Gilmour J, Evans W . Primary pulmonary hypertension. J Pathol Bacteriol. 2010; 58(4):687-97. DOI: 10.1002/path.1700580410. View

14.

Meyrick B, Reid L . Hypoxia and incorporation of 3H-thymidine by cells of the rat pulmonary arteries and alveolar wall. Am J Pathol. 1979; 96(1):51-70. PMC: 2042349. View

15.

Wang G, Semenza G . General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci U S A. 1993; 90(9):4304-8. PMC: 46495. DOI: 10.1073/pnas.90.9.4304. View

16.

Kasahara Y, Tuder R, Cool C, Lynch D, Flores S, Voelkel N . Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med. 2001; 163(3 Pt 1):737-44. DOI: 10.1164/ajrccm.163.3.2002117. View

17.

Moncada S, Gryglewski R, Bunting S, Vane J . An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature. 1976; 263(5579):663-5. DOI: 10.1038/263663a0. View

18.

Pietra G, Capron F, Stewart S, Leone O, Humbert M, Robbins I . Pathologic assessment of vasculopathies in pulmonary hypertension. J Am Coll Cardiol. 2004; 43(12 Suppl S):25S-32S. DOI: 10.1016/j.jacc.2004.02.033. View

19.

Palevsky H, Schloo B, Pietra G, Weber K, Janicki J, Rubin E . Primary pulmonary hypertension. Vascular structure, morphometry, and responsiveness to vasodilator agents. Circulation. 1989; 80(5):1207-21. DOI: 10.1161/01.cir.80.5.1207. View

20.

Tuder R, Chacon M, Alger L, Wang J, Taraseviciene-Stewart L, Kasahara Y . Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis. J Pathol. 2001; 195(3):367-74. DOI: 10.1002/path.953. View