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Detection of HBsAg, HBcAg, and HBV DNA in Ovarian Tissues from Patients with HBV Infection

Overview
Journal World J Gastroenterol
Publisher Baishideng Publishing Group
Specialty Gastroenterology
Date 2005 Oct 14
PMID 16222757
Citations 6
Authors
Li-Zhang Chen
Xue-Gong Fan
Jian-Ming Gao
Affiliations
Soon will be listed here.
Abstract

Aim: To investigate the presence of HBsAg, HBcAg, and HBV DNA in ovarian tissues from patients with HBV infection.

Methods: HBsAg and HBcAg were examined in ovarian biopsy tissues from 26 patients with HBV infection by immunocytochemistry, and HBV DNA was detected in ovarian tissues by PCR.

Results: HBsAg and HBcAg were present with the same positive rate of 34.6% (9/26). The total positive rate was 46.2% (12/26). HBsAg and HBcAg were positive in 6 (23.1%) of the 26 patients. Brown positive particles were diffusely distributed in ovarian cells. The positive rate of HBV DNA was 58.3% (7/12).

Conclusion: HBsAg, HBcAg, and HBV DNA can be detected in ovarian tissues from patients with HBV infection. The presence of HBsAg and HBcAg in ovarian tissues does not correlate with the HBV markers in serum.

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Detection of hepatitis B virus infection: A systematic review.

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Yu M, Jiang Q, Gu X, Ju L, Ji Y, Wu K PLoS One. 2013; 8(1):e54246.

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