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Insecticidal Anthranilic Diamides: a New Class of Potent Ryanodine Receptor Activators

Overview
Specialty Biochemistry
Date 2005 Sep 17
PMID 16165355
Citations 50
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Abstract

A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure-activity, and biological results are presented.

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