Molecular Characterization of the First Telithromycin-resistant Streptococcus Pneumoniae Isolate in Germany

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2005 Jul 29

PMID 16048973

Citations 13

Authors

Ralf Rene Reinert

Mark van der Linden

Adnan Al-Lahham

Affiliations

Soon will be listed here.

Abstract

A total of 486 Streptococcus pneumoniae isolates were collected in 2003 and 2004 in Germany and revealed the following resistance rates: penicillin G (7.2%) and erythromycin A (18.9%). Telithromycin exhibited good in vitro activity (MIC at which 90% of the isolates tested were inhibited, 0.125 microg/ml). However, one erm(B)-positive isolate was found to be telithromycin resistant (MIC, 8 microg/ml).

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