Successful Treatment of Fusarium Keratitis with Cornea Transplantation and Topical and Systemic Voriconazole

Overview

Journal Clin Infect Dis

Publisher Oxford University Press

Specialty Infectious Diseases

Date 2005 May 24

PMID 15909252

Citations 19

Authors

Rocus R Klont

Cathrien A Eggink

Antonius J M M Rijs

Pieter Wesseling

Paul E Verweij

Affiliations

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Abstract

A case of invasive Fusarium keratitis in a previously healthy male patient was treated successfully with cornea transplantation and systemic and topical voriconazole after treatment failure with topical amphotericin B and systemic itraconazole. Topical voriconazole was well tolerated, and, in conjunction with the oral administration, it resulted in a high level of the drug in the anterior chamber of the eye (which was 160% of the plasma drug level).

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