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Immuno-chemical Studies on Blood Groups; the Preparation of Blood Group A and B Substances and an Inactive Substance from Individual Horse Stomachs and of Blood Group B Substance from Human Saliva

Overview
Journal J Exp Med
Specialties Allergy & Immunology
General Medicine
Date 1950 Jan 1
PMID 15395576
Citations 9
Authors
H Baer
E A KABAT
V KNAUB
Affiliations
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Abstract

Blood group substances have been isolated from the saliva of human beings of blood group B and from the linings of individual horse stomachs. The properties of the human B substances are similar to those of hog and human blood group substances previously isolated. The horse substances showed lower hexosamine and reducing sugar and higher total and non-hexosamine nitrogen than do the materials from the other species. Materials isolated from individual horse stomachs possess either A or B activity or both. Certain stomachs yielded products of identical analytical composition but with neither blood group A, B, or O activity as measured by their ability to inhibit isoagglutination. Fucose has been identified as a constituent of the horse blood group substances.

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References
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