» Articles » PMID: 15215140

No Findings of Dental Defects in Children Treated with Minocycline

Overview
Specialty Pharmacology
Date 2004 Jun 25
PMID 15215140
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Forty-one children <8 years of age treated for brucellosis with oral minocycline (2.5 mg/kg) twice daily for 3 weeks were recalled and examined to check for dental staining and defects. Dental staining and defects were found in 14 of 41 exposed children (34.1%) and in 30 of 82 matched controls (36.6%), respectively (P > 0.2).

Citing Articles

Voltage-Gated Proton Channel Hv1 Regulates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson's Disease Models.

Neal M, Beier E, Hossain M, Boyle A, Zheng J, Kim C Antioxidants (Basel). 2023; 12(3).

PMID: 36978830 PMC: 10044828. DOI: 10.3390/antiox12030582.


Effect of Minocycline Pleurodesis in Infants With Refractory Chylothorax After Palliative Surgery for Complex Congenital Heart Disease.

Saito K, Saiki H, Tsuchiya S, Takizawa Y, Sato A, Goto T Cureus. 2022; 14(3):e23506.

PMID: 35494945 PMC: 9045464. DOI: 10.7759/cureus.23506.


Tigecycline-Induced Tooth Discoloration in Children Younger than Eight Years.

Zhu Z, Yu Q, Qi G, Yang J, Ni Y, Ruan W Antimicrob Agents Chemother. 2021; 65(9):e0085421.

PMID: 34228549 PMC: 8370207. DOI: 10.1128/AAC.00854-21.


Sensory Processing Phenotypes in Fragile X Syndrome.

Rais M, Binder D, Razak K, Ethell I ASN Neuro. 2018; 10:1759091418801092.

PMID: 30231625 PMC: 6149018. DOI: 10.1177/1759091418801092.


Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Post-Natal Day 17 Rats.

Simon D, Aneja R, Alexander H, Bell M, Bayir H, Kochanek P J Neurotrauma. 2017; 35(1):130-138.

PMID: 28699371 PMC: 5757077. DOI: 10.1089/neu.2017.5093.


References
1.
Cascio A, Scarlata F, Giordano S, Antinori S, Colomba C, Titone L . Treatment of human brucellosis with rifampin plus minocycline. J Chemother. 2003; 15(3):248-52. DOI: 10.1179/joc.2003.15.3.248. View

2.
Brearley L, Storey E . Tetracycline-induced tooth changes. 2. Prevalence, localization and nature of staining in extracted deciduous teeth. Med J Aust. 1968; 2(17):714-9. View

3.
GROSSMAN E, Walchek A, FREEDMAN H . Tetracyclines and permanent teeth: the relation between dose and tooth color. Pediatrics. 1971; 47(3):567-70. View

4.
Klein N, Cunha B . Tetracyclines. Med Clin North Am. 1995; 79(4):789-801. DOI: 10.1016/s0025-7125(16)30039-6. View

5.
Saivin S, Houin G . Clinical pharmacokinetics of doxycycline and minocycline. Clin Pharmacokinet. 1988; 15(6):355-66. DOI: 10.2165/00003088-198815060-00001. View