The Database of Interacting Proteins: 2004 Update

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2003 Dec 19

PMID 14681454

Citations 891

Authors

Lukasz Salwinski

Christopher S Miller

Adam J Smith

Frank K Pettit

James U Bowie

David Eisenberg

Affiliations

Soon will be listed here.

Abstract

The Database of Interacting Proteins (http://dip.doe-mbi.ucla.edu) aims to integrate the diverse body of experimental evidence on protein-protein interactions into a single, easily accessible online database. Because the reliability of experimental evidence varies widely, methods of quality assessment have been developed and utilized to identify the most reliable subset of the interactions. This CORE set can be used as a reference when evaluating the reliability of high-throughput protein-protein interaction data sets, for development of prediction methods, as well as in the studies of the properties of protein interaction networks.

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