A Decade of Caspases

Overview

Journal Oncogene

Specialties Molecular Biology
Oncology

Date 2003 Nov 25

PMID 14634618

Citations 348

Authors

Alexei Degterev

Michael Boyce

Junying Yuan

Affiliations

Soon will be listed here.

Abstract

Caspases are a family of cysteine proteases that play important roles in regulating apoptosis. A decade of research has generated a wealth of information on the signal transduction pathways mediated by caspases, the distinct functions of individual caspases and the mechanisms by which caspases mediate apoptosis and a variety of physiological and pathological processes.

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