Potential of Resveratrol to Combine with Hydrogel for Photodynamic Therapy Against Bacteria and Cancer-A Review

Overview

Journal Biomedicines

Specialty Biomedical Engineering

Date 2024 Sep 28

PMID 39335608

Authors

Siu Kan Law

Cris Wai Ching Liu

Christy Wing Sum Tong

Dawn Ching Tung Au

Affiliations

Soon will be listed here.

Abstract

Methods: Nine electronic databases, namely WanFang Data, PubMed, Science Direct, Scopus, Web of Science, Springer Link, SciFinder, and China National Knowledge Infrastructure (CNKI), were searched to conduct this literature review, without any regard to language constraints. Studies focusing on the photodynamic actions of hydrogel and Resveratrol were included that evaluated the effect of PDT against bacteria and cancer. All eligible studies were analyzed and summarized in this review.

Results: Resveratrol has antibacterial and anticancer effects. It can also act as PS in PDT or adjuvant but has some limitations. This is much better when combined with a hydrogel to enhance the effectiveness of PDT in the fight against bacteria and cancer.

Conclusions: Resveratrol combined with hydrogel is possible for PDT treatment in bacteria and cancer. They are compatible and reinforce each other to increase the effectiveness of PDT. However, much more work is required, such as cytotoxicity safety assessments of the human body and further enhancing the effectiveness of PDT in different environments for future investigations.

Citing Articles

Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings.

Alberts A, Tudorache D, Niculescu A, Grumezescu A Gels. 2025; 11(2).

PMID: 39996666 PMC: 11854827. DOI: 10.3390/gels11020123.

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