Assessment of Putative Protein Targets Derived from the SARS Genome

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 2003 Nov 19

PMID 14623076

Citations 11

Authors

Lisa Yan

Mikhail Velikanov

Paul Flook

Wenjin Zheng

Sandor Szalma

Scott Kahn

Affiliations

Soon will be listed here.

Abstract

The ability to rapidly and reliably develop hypotheses on the function of newly discovered protein sequences requires systematic and comprehensive analysis. Such an analysis, embodied within the DS GeneAtlas pipeline, has been used to critically evaluate the severe acute respiratory syndrome (SARS) genome with the goal of identifying new potential targets for viral therapeutic intervention. This paper discusses several new functional hypotheses on the roles played by the constituent gene products of SARS, and will serve as an example of how such assignments can be developed or extended on other systems of interest.

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