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Autologous Stimulation of Human Lymphocyte Subpopulation

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Journal J Exp Med
Date 1975 Nov 1
PMID 127826
Citations 92
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Abstract

The background stimulation universally seen when lymphocytes are cultured in vitro has been shown to be markedly lowered by reducing the proportion of B lymphocytes. B-rich fractions of lymphocytes had extremely high background stimulation. It is concluded that stimulation of T cells, probably by autologous B cells, provides the most probable explanation for the findings described.

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