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The Bacillus Subtilis Acyl Lipid Desaturase is a Delta5 Desaturase

Overview
Journal J Bacteriol
Publisher American Society for Microbiology
Specialty Microbiology
Date 2003 May 6
PMID 12730185
Citations 30
Authors
Silvia G Altabe
Pablo Aguilar
Gerardo M Caballero
Diego de Mendoza
Affiliations
Soon will be listed here.
Abstract

Bacillus subtilis was recently reported to synthesize unsaturated fatty acids (UFAs) with a double bond at positions delta5, delta7, and delta9 (M. H. Weber, W. Klein, L. Muller, U. M. Niess, and M. A. Marahiel, Mol. Microbiol. 39:1321-1329, 2001). Since this finding would have considerable importance in the double-bond positional specificity displayed by the B. subtilis acyl lipid desaturase, we have attempted to confirm this observation. We report that the double bond of UFAs synthesized by B. subtilis is located exclusively at the delta5 position, regardless of the growth temperature and the length chain of the fatty acids.

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