The Organization and Consequences of Eicosanoid Signaling

Overview

Journal J Clin Invest

Specialty General Medicine

Date 2003 Apr 17

PMID 12697726

Citations 55

Authors

Roy J Soberman

Peter Christmas

Affiliations

Soon will be listed here.

Citing Articles

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The clinical translation of eicosanoids and other oxylipins, although challenging, should be actively pursued.

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The CysLTR receptor mediates leukotriene C-driven acute and chronic itch.

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References

Moos P, Edes K, Fitzpatrick F . Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins. Proc Natl Acad Sci U S A. 2000; 97(16):9215-20. PMC: 16848. DOI: 10.1073/pnas.160241897. View

Jakobsson P, Thoren S, Morgenstern R, Samuelsson B . Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci U S A. 1999; 96(13):7220-5. PMC: 22058. DOI: 10.1073/pnas.96.13.7220. View

Miller D, Gillard J, Vickers P, Sadowski S, Leveille C, Mancini J . Identification and isolation of a membrane protein necessary for leukotriene production. Nature. 1990; 343(6255):278-81. DOI: 10.1038/343278a0. View

Yokomizo T, Izumi T, Chang K, Takuwa Y, Shimizu T . A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature. 1997; 387(6633):620-4. DOI: 10.1038/42506. View

Rouzer C, Ford-Hutchinson A, MORTON H, Gillard J . MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes. J Biol Chem. 1990; 265(3):1436-42. View

Israel E, Rubin P, Kemp J, Grossman J, Pierson W, SIEGEL S . The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med. 1993; 119(11):1059-66. DOI: 10.7326/0003-4819-119-11-199312010-00001. View

Glover S, de Carvalho M, Bayburt T, Jonas M, Chi E, Leslie C . Translocation of the 85-kDa phospholipase A2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigen. J Biol Chem. 1995; 270(25):15359-67. DOI: 10.1074/jbc.270.25.15359. View

Jakobsson P, Mancini J, Ford-Hutchinson A . Identification and characterization of a novel human microsomal glutathione S-transferase with leukotriene C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthase. J Biol Chem. 1996; 271(36):22203-10. DOI: 10.1074/jbc.271.36.22203. View

Robbiani D, Finch R, Jager D, Muller W, Sartorelli A, Randolph G . The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes. Cell. 2000; 103(5):757-68. DOI: 10.1016/s0092-8674(00)00179-3. View

10.

Gupta N, Nicholson D, Ford-Hutchinson A . Demonstration of cell-specific phosphorylation of LTC4 synthase. FEBS Lett. 1999; 449(1):66-70. DOI: 10.1016/s0014-5793(99)00397-x. View

11.

Bonventre J, Huang Z, Taheri M, OLeary E, Li E, Moskowitz M . Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2. Nature. 1997; 390(6660):622-5. DOI: 10.1038/37635. View

12.

Gijon M, Spencer D, Kaiser A, Leslie C . Role of phosphorylation sites and the C2 domain in regulation of cytosolic phospholipase A2. J Cell Biol. 1999; 145(6):1219-32. PMC: 2133140. DOI: 10.1083/jcb.145.6.1219. View

13.

Weiss J, Drazen J, Coles N, McFadden Jr E, Weller P, Corey E . Bronchoconstrictor effects of leukotriene C in humans. Science. 1982; 216(4542):196-8. DOI: 10.1126/science.7063880. View

14.

Lam B, Penrose J, Xu K, Baldasaro M, Austen K . Site-directed mutagenesis of human leukotriene C4 synthase. J Biol Chem. 1997; 272(21):13923-8. DOI: 10.1074/jbc.272.21.13923. View

15.

Welsch D, Creely D, Hauser S, Mathis K, Krivi G, Isakson P . Molecular cloning and expression of human leukotriene-C4 synthase. Proc Natl Acad Sci U S A. 1994; 91(21):9745-9. PMC: 44893. DOI: 10.1073/pnas.91.21.9745. View

16.

Honig S, Fu S, Mao X, Yopp A, Gunn M, Randolph G . FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. J Clin Invest. 2003; 111(5):627-37. PMC: 151892. DOI: 10.1172/JCI16200. View

17.

Ali A, Nicholson D, Ford-Hutchinson A . Characterization of human LTC4 synthase. Adv Prostaglandin Thromboxane Leukot Res. 1995; 23:171-3. View

18.

Rouzer C, Matsumoto T, Samuelsson B . Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. Proc Natl Acad Sci U S A. 1986; 83(4):857-61. PMC: 322969. DOI: 10.1073/pnas.83.4.857. View

19.

Kargman S, Vickers P, Evans J . A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells. J Cell Biol. 1992; 119(6):1701-9. PMC: 2289767. DOI: 10.1083/jcb.119.6.1701. View

20.

Khan S, SOROF S . Preferential binding of growth inhibitory prostaglandins by the target protein of a carcinogen. Proc Natl Acad Sci U S A. 1990; 87(23):9401-5. PMC: 55173. DOI: 10.1073/pnas.87.23.9401. View