Genome Organization and Molecular Analysis of the Temperate Bacteriophage MM1 of Streptococcus Pneumoniae

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2003 Mar 20

PMID 12644508

Citations 24

Authors

Virginia Obregon

Jose L Garcia

Ernesto Garcia

Rubens Lopez

Pedro Garcia

Affiliations

Soon will be listed here.

Abstract

The genome of MM1 (40,248 bp), a temperate bacteriophage from the Spain(23F)-1 multiresistant epidemic clone of Streptococcus pneumoniae, is organized in 53 open reading frames (ORFs) and in at least five functional clusters. Bioinformatic and N-terminal amino acid sequence analyses enabled the assignment of possible functions to 26 ORFs. Analyses comparing the MM1 genome with those of other bacteriophages revealed similarities, mainly with genomes of phages infecting gram-positive bacteria, which suggest recent exchange of genes between species colonizing the same habitat.

Citing Articles

: a Plethora of Temperate Bacteriophages With a Role in Host Genome Rearrangement.

Martin-Galiano A, Garcia E Front Cell Infect Microbiol. 2021; 11:775402.

PMID: 34869076 PMC: 8637289. DOI: 10.3389/fcimb.2021.775402.

Lysogeny in .

Garriss G, Henriques-Normark B Microorganisms. 2020; 8(10).

PMID: 33036379 PMC: 7600539. DOI: 10.3390/microorganisms8101546.

Methylation Warfare: Interaction of Pneumococcal Bacteriophages with Their Host.

Furi L, Crawford L, Rangel-Pineros G, Manso A, De Ste Croix M, Haigh R J Bacteriol. 2019; 201(19).

PMID: 31285240 PMC: 6755750. DOI: 10.1128/JB.00370-19.

The Bacteriophages of .

McShan W, McCullor K, Nguyen S Microbiol Spectr. 2019; 7(3).

PMID: 31111820 PMC: 11314938. DOI: 10.1128/microbiolspec.GPP3-0059-2018.

Puzzling Over the Pneumococcal Pangenome.

Hiller N, Sa-Leao R Front Microbiol. 2018; 9:2580.

PMID: 30425695 PMC: 6218428. DOI: 10.3389/fmicb.2018.02580.

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