Polymorphism for Dimerizing Ability at the Esterase-5 Locus in Drosophila Pseudoobscura

Overview

Journal Genetics

Publisher Oxford University Press

Specialty Genetics

Date 1976 Jan 1

PMID 1248736

Citations 17

Authors

G Cobbs

Affiliations

Soon will be listed here.

Abstract

Three new alleles are reported at the esterase-5 locus of Drosophila pseudoobscura. All three of these alleles are different from those previously reported in their ability to dimerize. One allele will not form heterodimers or homodimers and exists only as a monomer. A second allele does form heterodimers but will not form homodimers. The third allele forms both hetero- and homodimers as well as forming monomers. Estimates of the frequency of these alleles in a natural population are given. The existence of these is discussed with respect to recently proposed models for a molecular mechanism for heterosis.

Citing Articles

Kidney esterases of Mus musculus: further polymorphism of esterase-6, esterase-9, and a new esterase, esterase-20.

Nash H, von DEIMLING O Biochem Genet. 1982; 20(5-6):537-54.

PMID: 7115286 DOI: 10.1007/BF00484703.

Substrate-preference polymorphism at an esterase locus of Drosophila mojavensis.

Zouros E, van Delden W Genetics. 1982; 100(2):307-14.

PMID: 7106559 PMC: 1201813. DOI: 10.1093/genetics/100.2.307.

Tissue localization of esterase-5 in Drosophila pseudoobscura.

Lunday A, FARMER J Biochem Genet. 1983; 21(5-6):453-63.

PMID: 6870773 DOI: 10.1007/BF00484438.

Assessment of variability within electromorphs of alcohol dehydrogenase in Drosophila melanogaster.

Kreitman M Genetics. 1980; 95(2):467-75.

PMID: 6781981 PMC: 1214240. DOI: 10.1093/genetics/95.2.467.

Dynamics of phosphoglucomutase heat sensitivity polymorphism in Culicidae.

Trippa G, Scozzari R, Cicchetti R Experientia. 1980; 36(2):174-6.

PMID: 6445279 DOI: 10.1007/BF01953715.

References

Berger E . Esterases of Drosophila. II. Biochemical studies of esterase-5 in D. pseudoobscura. Genetics. 1974; 78(4):1157-72. PMC: 1213244. DOI: 10.1093/genetics/78.4.1157. View

Macintyre R . Evolution of acid phosphatase-1 in the genus Drosophila as estimated by subunit hybridization I: methodology. Genetics. 1971; 68(4):483-508. PMC: 1212671. DOI: 10.1093/genetics/68.4.483. View

Hubby J, NARISE S . Protein differences in Drosophila. 3. Allelic differences and species differences in in vitro hybrid enzyme formation. Genetics. 1967; 57(2):291-300. PMC: 1211727. DOI: 10.1093/genetics/57.2.291. View

Noyes B, Glatthaar B, Garavelli J, Bradshaw R . Structural and functional similarities between mitochondrial malate dehydrogenase and L-3-hydroxyacyl CoA dehydrogenase. Proc Natl Acad Sci U S A. 1974; 71(4):1334-8. PMC: 388222. DOI: 10.1073/pnas.71.4.1334. View

NARISE S, Hubby J . Purification of esterase-5 from Drosophila pseudoobscura. Biochim Biophys Acta. 1966; 122(2):281-8. DOI: 10.1016/0926-6593(66)90068-3. View