Glycine-specific Synapses in Rat Spinal Cord. Identification by Electron Microscope Autoradiography

Overview

Journal J Cell Biol

Specialty Cell Biology

Date 1976 Feb 1

PMID 1245552

Citations 5

Authors

D L Price

A STOCKS

J W Griffin

A Young

K Peck

Affiliations

Soon will be listed here.

Abstract

Glycine, an inhibitory transmitter in spinal cord, is taken up into specific nerve terminals by means of a unique high-affinity uptake system. In this study, [3H]glycine was directly microinjected into rat ventral horn in vivo and electron microscope autoradiography used to localize the label in various anatomic compartments. Quantiative analysis showed that [3H]glycine labeled a high proportion of axosomatic and axodendritic synapses which presumably act to inhibit spinal motor neurons.

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The uptake and release of [3H]glycine in the goldfish retina.

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