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The Multiligand Receptor RAGE As a Progression Factor Amplifying Immune and Inflammatory Responses

Overview
Journal J Clin Invest
Specialty General Medicine
Date 2001 Oct 3
PMID 11581294
Citations 451
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References
1.
Kislinger T, Fu C, Huber B, Qu W, Taguchi A, Du Yan S . N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. J Biol Chem. 1999; 274(44):31740-9. DOI: 10.1074/jbc.274.44.31740. View

2.
Fraser I, Koziel H, Ezekowitz R . The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity. Semin Immunol. 1998; 10(5):363-72. DOI: 10.1006/smim.1998.0141. View

3.
Lalla E, Lamster I, Feit M, Huang L, Spessot A, Qu W . Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice. J Clin Invest. 2000; 105(8):1117-24. PMC: 300834. DOI: 10.1172/JCI8942. View

4.
Taguchi A, Blood D, Del Toro G, Canet A, Lee D, Qu W . Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. Nature. 2000; 405(6784):354-60. DOI: 10.1038/35012626. View

5.
Yan S, Zhu H, Zhu A, Golabek A, Du H, Roher A . Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis. Nat Med. 2000; 6(6):643-51. DOI: 10.1038/76216. View