Signal Transduction. An Arresting Start for MAPK

Overview

Journal Science

Specialty Science

Date 2001 Feb 24

PMID 11185509

Citations 12

Authors

J Pouyssegur

Affiliations

Soon will be listed here.

Abstract

Exactly how signaling proteins know where they need to be in the cell is one of the intriguing mysteries of signal transduction biology. In a Perspective, Pouysségur reviews new results that identify b-arrestin 2 as a scaffolding protein that holds together the different components of a MAPK signaling pathway that activates the transcription factor kinase, JNK3.

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