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Secret Sharers in the Immune System: a Novel RNA Editing Activity Links Switch Recombination and Somatic Hypermutation

Overview
Journal Genome Biol
Specialties Biology
Genetics
Date 2001 Feb 24
PMID 11178252
Authors
Affiliations
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Abstract

A new mechanism for regulation in the immune system has been identified: a cytidine deaminase is critical for both class switch recombination and somatic hypermutation, revealing an unanticipated link between these two processes.

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