V(D)J Recombination: on the Cutting Edge

Overview

Journal Curr Opin Cell Biol

Publisher Elsevier

Specialty Cell Biology

Date 1999 Jul 8

PMID 10395566

Citations 21

Authors

M A Oettinger

Affiliations

Soon will be listed here.

Abstract

The vertebrate immune system has evolved an elegant mechanism for generating an enormous diversity in antigen receptor binding specificity from a limited amount of genetic information. Recent advances are rapidly increasing our understanding of this unusual site-specific DNA rearrangement that assembles the antigen receptor genes during lymphoid development.

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